Natural product inhibited anti-inflammatory mediator release from human airway epithelial cells
Homing in on mechanisms for the reported effectiveness of resveratrol, which is found in red wine, researchers at Imperial College London, England, confirmed its broad anti-inflammatory action, and found potential for applications in chronic obstructive pulmonary disease (COPD), asthma, and possibly even arthritis. Clinical preparation and delivery remain issues, though an aerosol version would have obvious benefits.
Indeed, lead researcher Louise Donnelly said "Resveratrol exhibited anti-inflammatory activity in all the systems we examined: laboratory cells lines as well as ’real’ human airway epithelial cells," or HAEC. The research paper published by Donnelly et al. in the American Journal of Physiology-Lung Cellular and Molecular Physiology, notes: "Our study is novel as it examines the anti-inflammatory mechanism(s) of resveratrol in cells relevant to human disease and explores all of the proposed mechanisms in a single study."
Mayer Resnick | EurekAlert!
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