Women under 35 years of age with breast cancer can have an almost 20% lower risk of their disease recurring if they are treated using a new radiotherapy regime. These were some of the results presented here today (Tuesday 26th October) by Prof Harry Bartelink and his colleagues at the 23rd Meeting of the European Society for Therapeutic Radiology and Oncology.
The analyses were based on data from the EORTC (European Organisation for Research and Treatment of Cancer) 22881 trial with updated follow-up (median follow-up: > 6years). 5318 patients with microscopically complete excision of early breast cancer using breast-conserving surgery were randomly assigned to undergo 50Gy irradiation of the whole breast either with or without an additional 16Gy of radiotherapy to the tumour bed (radiotherapy boost). 362 local recurrences were observed: 232 in the no-boost group and 130 in the boost group, demonstrating a considerable improvement in recurrence rate in women treated with boost.
The effect of the boost treatment was of greatest benefit in the younger women, with a reduction in 5-year local disease recurrence rate from 26% to 8.5% in women under 35 years of age. In women over 60 the boost dose resulted in a reduction of 5-year local recurrence rate from 3.9% to 2.1%. The addition of a boost dose caused a slight increase in early and late side effects and increases the burden on already overstretched resources. A balance therefore needs to be struck between providing optimal care with acceptable side effects whilst taking into account the availability of resources.
Stuart Bell | alfa
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23.03.2018 | Institut Pasteur
Scientists develop tiny tooth-mounted sensors that can track what you eat
22.03.2018 | Tufts University
Satellites in near-Earth orbit are at risk due to the steady increase in space debris. But their mission in the areas of telecommunications, navigation or weather forecasts is essential for society. Fraunhofer FHR therefore develops radar-based systems which allow the detection, tracking and cataloging of even the smallest particles of debris. Satellite operators who have access to our data are in a better position to plan evasive maneuvers and prevent destructive collisions. From April, 25-29 2018, Fraunhofer FHR and its partners will exhibit the complementary radar systems TIRA and GESTRA as well as the latest radar techniques for space observation across three stands at the ILA Berlin.
The "traffic situation" in space is very tense: the Earth is currently being orbited not only by countless satellites but also by a large volume of space...
An international team of researchers has discovered a new anti-cancer protein. The protein, called LHPP, prevents the uncontrolled proliferation of cancer cells in the liver. The researchers led by Prof. Michael N. Hall from the Biozentrum, University of Basel, report in “Nature” that LHPP can also serve as a biomarker for the diagnosis and prognosis of liver cancer.
The incidence of liver cancer, also known as hepatocellular carcinoma, is steadily increasing. In the last twenty years, the number of cases has almost doubled...
In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.
Following the loss of radio contact with Tiangong-1 in 2016 and due to the low orbital height, it is now inevitable that the Chinese space station will...
Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.
They are united in their passion for OLED (organic light emitting diodes) lighting with all of its unique facets and application possibilities. Thus experts in...
A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...
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