Mayo Clinic neurologists have discovered a drug application smart enough to alleviate orthostatic hypotension -- problems with sinking blood pressure when standing up from a sitting position -- without the unwanted effect of also causing patients blood pressure to soar when lying down.
"This is a significant step forward for these patients," says Phillip Low, M.D., Mayo Clinic neurologist and lead study investigator. "This would be a good drug to provide the first line of treatment."
The drug, pyridostigmine, has been used for years for myasthenia gravis, a neuromuscular transmission disorder. Dr. Low hypothesized that it would also improve nerve cell transmission for orthostatic hypotension patients and trigger the reflex that controls blood pressure in all positions.
Lisa Lucier | EurekAlert!
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