Differentiated thyroid cancer, the most common form of thyroid cancer, is one of the success stories in the war on cancer. Since the advent of radioiodine therapy, it has been considered one of the most curable cancers. On the downside, current treatment involves taking patients off their thyroid medication. This can lead to serious side effects including symptoms of hypothyroidism, an unbalanced metabolic state that can induce fatigue, depression, and other unpleasant conditions.
Bart de Keizer, MD, and a team from the University Medical Center in Utrecht, The Netherlands, and Ghent University Hospital, Belgium, reported in the September issue of The Journal of Nuclear Medicine, on a new technique that allows patients to maintain their normal course of thyroid medication prior to and during radioiodine therapy. The new technique avoids the problems of hypothyroidism, and levels of radiation in the blood and bone marrow remain well below the accepted safety thresholds during therapy.
Currently, thyroid cancer patients who have had their thyroid removed are treated with radioactive iodine, which effectively zeros in on and kills any remaining cancerous thyroid cells. But prior to radioiodine treatment, the patient must be taken off thyroid hormone replacement medication for up to 6 weeks. The withdrawal of thyroid medication signals the body to produce thyroid stimulating hormone (THS). TSH causes any remaining or metastasized thyroid cells to quickly absorb the radioactive iodine when it is administered, in effect forcing the cancerous cells to absorb lethal radioactive molecules that are largely ignored by other cells in the body.
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Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.
The results will be published on March 22 in the journal „Astronomy & Astrophysics“.
Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...
Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.
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In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.
Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to simulate these confined natural conditions in artificial vesicles for the first time. As reported in the academic journal Small, the results are offering better insight into the development of nanoreactors and artificial organelles.
Enzymes behave differently in a test tube compared with the molecular scrum of a living cell. Chemists from the University of Basel have now been able to...
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