Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Injectable Soft Tissue Implant Material Appears Effective in Facial Plastic Surgery

21.07.2004


The use of an injectable implant material appears effective and well tolerated by patients undergoing facial soft tissue augmentation, and patient satisfaction with treatment is high, according to an article in the July/August issue of The Archives of Facial Plastic Surgery, one of the JAMA/Archives journals.



According to information in the article, plastic and reconstructive surgery is among several clinical indications for soft tissue augmentation. According to the article, all the components of this material have been extensively used in implants and drug delivery systems, and its biocompatibility has been tested extensively in preclinical studies.

Thomas L. Tzikas, M.D., who is in private practice in Delray Beach, Fla., evaluated the clinical efficacy and patient satisfaction of a new product developed for soft tissue augmentation (Radiance FN). Dr. Tzikas studied 90 patients, aged 25 to 85, who underwent soft tissue injections with the product. The primary areas treated were lips, nasolabial (nose and upper lip) folds, glabellar rhytids (skin wrinkles in the area between the eyebrows), marionette lines (lines at the corner of the mouth), prejowl depressions, acne scars, and surgical soft tissue defects. Patients were surveyed after treatment and for up to six months for pain, ecchymosis (skin discoloration caused by the escape of blood into the tissues from ruptured blood vessels), skin erythema (redness resulting from inflammation), nodules (small lumps, swelling, or collection of tissue), softness, appearance, and satisfaction.


“In terms of efficacy, at six months, appearance, softness, and overall patient satisfaction were rated good or excellent in 74 percent, 80 percent, and 88 percent of patients, respectively,” Dr. Tzikas writes.

“Moderate or severe pain occurred with injection in 59 percent of patients, but disappeared two to five minutes after injection,” he continues. “Erythema, edema [excess fluid in the tissues], and ecchymosis were common immediately after treatment but resolved in all patients within two weeks. Seven patients had persistent visible mucosal lip nodules, four of whom required intervention.”

This product has been used for facial plastic surgery in more than 5,000 patients in the United States, Argentina, and Italy, but the follow-up to date has only been approximately three years. Dr. Tzikas suggests several questions remain regarding its use.

“Are there long-term adverse reactions associated with treatment?” he asks. “Does the implant stay soft in the face in the long term? How predictable is its use in mobile regions of the face?”

“As we gain additional experience with this promising new material, we will be better able to determine its most appropriate use and long-term safety profile,” he concludes.

| newswise
Further information:
http://www.ama-assn.org
http://archfacial.com

More articles from Health and Medicine:

nachricht GLUT5 fluorescent probe fingerprints cancer cells
20.04.2018 | Michigan Technological University

nachricht Scientists re-create brain neurons to study obesity and personalize treatment
20.04.2018 | Cedars-Sinai Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Spider silk key to new bone-fixing composite

University of Connecticut researchers have created a biodegradable composite made of silk fibers that can be used to repair broken load-bearing bones without the complications sometimes presented by other materials.

Repairing major load-bearing bones such as those in the leg can be a long and uncomfortable process.

Im Focus: Writing and deleting magnets with lasers

Study published in the journal ACS Applied Materials & Interfaces is the outcome of an international effort that included teams from Dresden and Berlin in Germany, and the US.

Scientists at the Helmholtz-Zentrum Dresden-Rossendorf (HZDR) together with colleagues from the Helmholtz-Zentrum Berlin (HZB) and the University of Virginia...

Im Focus: Gamma-ray flashes from plasma filaments

Novel highly efficient and brilliant gamma-ray source: Based on model calculations, physicists of the Max PIanck Institute for Nuclear Physics in Heidelberg propose a novel method for an efficient high-brilliance gamma-ray source. A giant collimated gamma-ray pulse is generated from the interaction of a dense ultra-relativistic electron beam with a thin solid conductor. Energetic gamma-rays are copiously produced as the electron beam splits into filaments while propagating across the conductor. The resulting gamma-ray energy and flux enable novel experiments in nuclear and fundamental physics.

The typical wavelength of light interacting with an object of the microcosm scales with the size of this object. For atoms, this ranges from visible light to...

Im Focus: Basel researchers succeed in cultivating cartilage from stem cells

Stable joint cartilage can be produced from adult stem cells originating from bone marrow. This is made possible by inducing specific molecular processes occurring during embryonic cartilage formation, as researchers from the University and University Hospital of Basel report in the scientific journal PNAS.

Certain mesenchymal stem/stromal cells from the bone marrow of adults are considered extremely promising for skeletal tissue regeneration. These adult stem...

Im Focus: Like a wedge in a hinge

Researchers lay groundwork to tailor drugs for new targets in cancer therapy

In the fight against cancer, scientists are developing new drugs to hit tumor cells at so far unused weak points. Such a “sore spot” is the protein complex...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

IWOLIA: A conference bringing together German Industrie 4.0 and French Industrie du Futur

09.04.2018 | Event News

 
Latest News

Magnetic nano-imaging on a table top

20.04.2018 | Physics and Astronomy

Start of work for the world's largest electric truck

20.04.2018 | Interdisciplinary Research

Atoms may hum a tune from grand cosmic symphony

20.04.2018 | Physics and Astronomy

VideoLinks
Science & Research
Overview of more VideoLinks >>>