A Mayo Clinic discovery about a protein known as Dynamin-2 has thrown conventional wisdom for a loop. Finding the protein on the centrosome, a minute structure near a cell’s nucleus, may lead to new strategies for stopping cancer growth.
The Mayo team, already known for discovering several families of dynamins, this time discovered them -- not on a membrane, as expected -- but on the unlikely centrosome which has no membrane. It was the last place they expected to find them, but the surprise finding offers a new lead in the fight against cancer.
"These findings provide us with a basic understanding of how normal and cancer cells are organized; how they divide and how they might grow and die -- which is an important part of cancer," says Mark McNiven, Ph.D., the cell biologist who led the Mayo Clinic research team’s investigation. "A lot of cancers, you could argue, don’t grow faster; they just don’t die. So this discovery will improve our understanding of this very relevant cellular process. It promotes understanding the cell at its most basic level, giving us a new layer of detail."
Bob Nellis | Mayo Clinic
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More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
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