Genes that help wounds heal are most often the "good guys," but a new study paints them as the enemy in some types of cancer. Researchers at the Stanford University School of Medicine have found that some tumors activate these wound-healing genes and, when they do, the tumors are more likely to spread. This work could help highlight new ways to treat the disease along with helping doctors decide which cancers to approach more aggressively.
"This is a feature we can find early on in the disease and it could change the way cancer is treated," said Howard Chang, MD, PhD, a postdoctoral scholar and lead author of the paper. The work appears in the Jan. 19 edition of Public Library of Science Biology.
The research group, led by Patrick Brown, MD, PhD, professor of biochemistry, took an unusual approach in finding the telltale genes. In most studies, scientists analyze tumor samples and look for genes that are more active compared to normal tissue. Such studies have produced long lists of genes involved in cancer biology but dont provide clues about what role those genes may be playing.
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For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...
For photographers and scientists, lenses are lifesavers. They reflect and refract light, making possible the imaging systems that drive discovery through the microscope and preserve history through cameras.
But today's glass-based lenses are bulky and resist miniaturization. Next-generation technologies, such as ultrathin cameras or tiny microscopes, require...
Scientists from the University of Zurich have succeeded for the first time in tracking individual stem cells and their neuronal progeny over months within the intact adult brain. This study sheds light on how new neurons are produced throughout life.
The generation of new nerve cells was once thought to taper off at the end of embryonic development. However, recent research has shown that the adult brain...
Theoretical physicists propose to use negative interference to control heat flow in quantum devices. Study published in Physical Review Letters
Quantum computer parts are sensitive and need to be cooled to very low temperatures. Their tiny size makes them particularly susceptible to a temperature...
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