Harvard Medical School researchers have uncovered an ovary gene whose absence from mouse egg cells produced severe pregnancy complications. The gene, Fmn2, which produces the protein formin-2, is similar in mice and humans and offers promise for understanding embryo loss, birth defects, and infertility in women. The study appears in the December Nature Cell Biology.
"As humans we are incredibly bad at producing eggs with the normal number of chromosomes, which is the leading cause of pregnancy loss in women," says Benjamin Leader, an HMS MD/PhD candidate, and the papers lead author. "The biological means for ensuring proper distribution of chromosomes to the egg has been difficult to determine.
"Our study shows that the formin-2 gene is required in order to ensure the proper distribution of chromosomes to the egg. About one percent of women suffer from recurrent pregnancy loss, which can be defined as a loss of greater than two or three pregnancies. We are now actively searching for mutations involving the formin-2 gene in women with reproductive loss and infertility," Leader added.
Donna Burtanger | EurekAlert!
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Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
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In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
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A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
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