Flavonoids that are found in fruit, vegetables, chocolate, tea, wine, and grape juice reduce cellular oxidative stress and are associated with a reduced risk of heart disease and cancer. Concord grape juice is a rich source of flavonoids, but it has not been compared to antioxidant supplements in terms of its efficacy in reducing oxidative stress. In an article in the American Journal of Clinical Nutrition, OByrne et al. compared the effects of Concord grape juice (CGJ) and antioxidant supplements in a group of healthy subjects, and found that CGJ is a potent, long-lasting antioxidant that compares favorably to supplements in its action and perhaps has unique properties that supplements do not.
The 32 participants, who were all healthy and averaged 28 years old, were assigned to receive 400 IU of á-tocopherol (an antioxidant supplement), or 10 mL per day of 100% CGJ over a 2-week period. Prior to and throughout the study, the subjects were on a flavonoid-restricted diet to ensure that the primary source of flavonoids in their diets was either from the grape juice or the supplements, and fasting blood samples were collected before, during, and after the study period. Both CJG and antioxidant supplements provided significant antioxidant protection to serum, plasma proteins, and low-density lipoproteins (LDL). A unique finding was that CGJ has a previously unknown antioxidant capability of reducing the concentration of oxidized protein in the blood by 20%, which the supplements did not.
The authors suggest that future studies should investigate the long-term antioxidant effects of CJD in combination with a well-defined diet. CGJ is a popular beverage that could provide an everyday method for prevention of chronic disease in all age groups.
Elizabeth Horowitz | EurekAlert!
Investigators may unlock mystery of how staph cells dodge the body's immune system
22.09.2017 | Cedars-Sinai Medical Center
Monitoring the heart's mitochondria to predict cardiac arrest?
21.09.2017 | Boston Children's Hospital
Plants and algae use the enzyme Rubisco to fix carbon dioxide, removing it from the atmosphere and converting it into biomass. Algae have figured out a way to increase the efficiency of carbon fixation. They gather most of their Rubisco into a ball-shaped microcompartment called the pyrenoid, which they flood with a high local concentration of carbon dioxide. A team of scientists at Princeton University, the Carnegie Institution for Science, Stanford University and the Max Plank Institute of Biochemistry have unravelled the mysteries of how the pyrenoid is assembled. These insights can help to engineer crops that remove more carbon dioxide from the atmosphere while producing more food.
A warming planet
Our brains house extremely complex neuronal circuits, whose detailed structures are still largely unknown. This is especially true for the so-called cerebral cortex of mammals, where among other things vision, thoughts or spatial orientation are being computed. Here the rules by which nerve cells are connected to each other are only partly understood. A team of scientists around Moritz Helmstaedter at the Frankfiurt Max Planck Institute for Brain Research and Helene Schmidt (Humboldt University in Berlin) have now discovered a surprisingly precise nerve cell connectivity pattern in the part of the cerebral cortex that is responsible for orienting the individual animal or human in space.
The researchers report online in Nature (Schmidt et al., 2017. Axonal synapse sorting in medial entorhinal cortex, DOI: 10.1038/nature24005) that synapses in...
Whispering gallery mode (WGM) resonators are used to make tiny micro-lasers, sensors, switches, routers and other devices. These tiny structures rely on a...
Using ultrafast flashes of laser and x-ray radiation, scientists at the Max Planck Institute of Quantum Optics (Garching, Germany) took snapshots of the briefest electron motion inside a solid material to date. The electron motion lasted only 750 billionths of the billionth of a second before it fainted, setting a new record of human capability to capture ultrafast processes inside solids!
When x-rays shine onto solid materials or large molecules, an electron is pushed away from its original place near the nucleus of the atom, leaving a hole...
For the first time, physicists have successfully imaged spiral magnetic ordering in a multiferroic material. These materials are considered highly promising candidates for future data storage media. The researchers were able to prove their findings using unique quantum sensors that were developed at Basel University and that can analyze electromagnetic fields on the nanometer scale. The results – obtained by scientists from the University of Basel’s Department of Physics, the Swiss Nanoscience Institute, the University of Montpellier and several laboratories from University Paris-Saclay – were recently published in the journal Nature.
Multiferroics are materials that simultaneously react to electric and magnetic fields. These two properties are rarely found together, and their combined...
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22.09.2017 | Physics and Astronomy
22.09.2017 | Physics and Astronomy