QRisk2, an equation developed to help doctors identify those most at risk of developing CVD for the first time, simultaneously takes into account extra risk from ethnicity, social deprivation and other clinical conditions such as family history of heart disease or diabetes.
The study, to develop QRisk2, was undertaken by QResearch — a not-for-profit partnership between The University of Nottingham and leading primary care systems supplier, EMIS.
Researchers from the Universities of Edinburgh and Queen Mary's and from Bristol and Medway Primary Care Trusts also supported the project.
Doctors will be able to use this information to help decide how best to target patients with preventative measures such as lifestyle advice and cholesterol-lowering treatments.
The research reveals that certain ethnic groups are at much greater risk than the general population, with men of Pakistani background being nearly twice as likely to suffer a heart attack or stroke. For Bangladeshi men, the risk increases by nearly 70 per cent.
The National Institute for Clinical Excellence (NICE) recommends that the Framingham equation, based on American data from a predominantly white population, be modified to take into account the increased risk in South Asian men. However, no adjustment is recommended for South Asian women.
QRisk2 identifies the risk of CVD in this portion of the population, indicating that in Indian, Pakistani and Bangladeshi women, the risk is 43 per cent, 80 per cent and 35 per cent higher, respectively, than in the background population.
Commenting on the research published on BMJ.com today, QRisk2 project leader, Professor Julia Hippisley-Cox of The University of Nottingham, said: “Based on the study of 15 years of data from over 2 million UK patients, QRisk2 is a contemporary and specific risk score that allows CVD risk to be personalised to the individual patient.
“Qrisk2 has been developed for GPs, by GPs and without the co-operation of the thousands of working GPs who freely contribute their data to QResearch, projects like QRisk2 could not happen.”
Dr David Stables, Clinical Director of EMIS and a Director of Qresearch, said: “QRisk2 is likely to be a more efficient tool for treatment decisions, supporting the primary prevention of cardiovascular disease.
“We are currently working on software that will enable GPs to implement QRisk2 easily within clinical practice.”
The study comes as the Government's health watchdog, NICE, recommends a systematic identification of people with a 20 per cent chance of developing heart disease in the next 10 years. The Government is investing an extra £500 million to support this work.
Researchers release the brakes on the immune system
18.10.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
Norovirus evades immune system by hiding out in rare gut cells
12.10.2017 | University of Pennsylvania School of Medicine
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...
17.10.2017 | Event News
10.10.2017 | Event News
10.10.2017 | Event News
20.10.2017 | Information Technology
20.10.2017 | Materials Sciences
20.10.2017 | Interdisciplinary Research