Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Severe West Nile infection could lead to lifetime of symptoms

19.03.2008
Most people who suffer severe infection with West Nile virus still experience symptoms years after infection and many may continue to experience these symptoms for the rest of their lives according to research presented today (March 17) at the 2008 International Conference on Emerging Infectious Diseases in Atlanta, Georgia.

“What we are finding is that about 60% of people, one year after severe infection with West Nile, still report symptoms,” says Kristy Murray of the University of Texas Health Science Center at Houston, a lead researcher on the study.

Supported by a grant from the National Institutes of Health (NIH), Murray and her colleagues have been conducting a long-term, in-depth study of people in the Houston, Texas area who have been diagnosed with West Nile. They monitored 108 patients over a 5-year period, checking in every 6 months to record both subjective and objective clinical outcomes and rates of recovery.

Persistent symptoms of West Nile infection still plagued 60% of patients in the study at the end of the first year. Moreover, Murray and her colleagues discovered that most, if not all, recovery appeared to take place in the first two years following infection.

“Once they hit two years it completely plateaus. If a patient has not recovered by that time, it is very likely the will never recover,” says Murray. Appoximately 40% of patients in the study continued to experience symptoms 5 years after infection. Some long-term damage included memory loss, loss of balance and tremors.

Approximately 80 percent of people who are infected with West Nile do not experience symptoms. This study only included patients with symptoms, which can range from mild fatigue and weakness to seizures, paralysis and tremors. Half the patients experienced encephalitis due to infection and another third presented with meningitis. Murray and her colleagues noted a significant difference in recovery rates.

“Those patients with ecephalitis were less likely to recover than those who had meningitis or uncomplicated fever,” says Murray.

Another outcome of severe West Nile infection was depression. At the one-year followup 31% of the patients reported new-onset depression. Using objective measurements, the researchers determined that 75% of those cases met the definition of clinical depression.

“West Nile virus infection can result in significant long-term clinical sequelae and cognitive and functional impairment, particularly in those who present with encephalitis,” says Murray.

Jim Sliwa | EurekAlert!
Further information:
http://www.asmusa.org
http://www.iceid.org

More articles from Health and Medicine:

nachricht Correct connections are crucial
26.06.2017 | Charité - Universitätsmedizin Berlin

nachricht One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Study shines light on brain cells that coordinate movement

26.06.2017 | Life Sciences

Smooth propagation of spin waves using gold

26.06.2017 | Physics and Astronomy

Switchable DNA mini-machines store information

26.06.2017 | Information Technology

VideoLinks
B2B-VideoLinks
More VideoLinks >>>