Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Nerve block eases troublesome hot flashes

05.02.2014
Randomized, controlled trial shows anesthetic could be alternative to hormones and other medications

Injecting a little anesthetic near a nerve bundle in the neck cut troublesome hot flashes significantly, shows a new randomized, controlled trial published online today in Menopause, the journal of The North American Menopause Society (NAMS). The technique could give women who cannot or prefer not to take hormones or other medications an effective treatment alternative.

In this study from two Chicago medical schools, Northwestern University and the University of Illinois at Chicago, 40 women who had moderate to severe hot flashes got either a stellate ganglion block—an injection of tiny amounts of anesthetic near a nerve bundle in the neck—or an injection of plain saline solution.

Both groups of women kept diaries of the frequency and severity of their hot flashes from two weeks before the injection until six months afterward. In addition, for 24 hours at the start of the study and three months after the injection, the women wore skin conductance monitors, which measured hot flashes objectively and also let the women record when they felt a hot flash.

On average, the women had 10 hot flashes a day, rating two-thirds of them moderate or severe. (Hot flashes lasting up to 15 minutes with symptoms such as perspiration, clammy skin, dry mouth, tense muscles, and rapid heartbeat were considered "moderate." Hot flashes lasting up to 20 minutes with symptoms such as "raging furnace" warmth, weakness, feeling faint, extreme perspiration, and heart irregularities were considered "severe.")

Four to six months after the injection, the total number of hot flashes wasn't significantly different between the real- and sham-treated groups, but the number of moderate to severe hot flashes was cut in half for women who got the real nerve block (52%) compared with just 4% for the women who got the sham injection. What's more, the intensity of the hot flashes dropped 38% for the women who got the real nerve block, compared with just 8% for those who got the sham injection.

"A few small studies suggested that this treatment had potential, but this is the first study to show that this hot flash treatment really is better than placebo. The nerve blocks could prove very helpful for women with a history of breast cancer, as well as for women who prefer not to use hormones or other drugs for hot flashes," says NAMS Executive Director Margery Gass, MD.

The study, "Effects of stellate ganglion block on vasomotor symptoms: findings from a randomized controlled clinical trial in postmenopausal women," was supported by the Department of Obstetrics and Gynecology, Northwestern University and grants from the National Institute of Child Health and Human Development and the National Institutes of Health Office of Research on Women's Health and will be published in the August 2014 print edition of Menopause.

Founded in 1989, The North American Menopause Society (NAMS) is North America's leading nonprofit organization dedicated to promoting the health and quality of life of all women during midlife and beyond through an understanding of menopause and healthy aging. Its multidisciplinary membership of 2,000 leaders in the field—including clinical and basic science experts from medicine, nursing, sociology, psychology, nutrition, anthropology, epidemiology, pharmacy, and education—makes NAMS uniquely qualified to serve as the definitive resource for health professionals and the public for accurate, unbiased information about menopause and healthy aging.

Eileen Petridis | EurekAlert!
Further information:
http://www.menopause.org

More articles from Health and Medicine:

nachricht One gene closer to regenerative therapy for muscular disorders
01.06.2017 | Cincinnati Children's Hospital Medical Center

nachricht The gut microbiota plays a key role in treatment with classic diabetes medication
01.06.2017 | University of Gothenburg

All articles from Health and Medicine >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

Im Focus: Optoelectronic Inline Measurement – Accurate to the Nanometer

Germany counts high-precision manufacturing processes among its advantages as a location. It’s not just the aerospace and automotive industries that require almost waste-free, high-precision manufacturing to provide an efficient way of testing the shape and orientation tolerances of products. Since current inline measurement technology not yet provides the required accuracy, the Fraunhofer Institute for Laser Technology ILT is collaborating with four renowned industry partners in the INSPIRE project to develop inline sensors with a new accuracy class. Funded by the German Federal Ministry of Education and Research (BMBF), the project is scheduled to run until the end of 2019.

New Manufacturing Technologies for New Products

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

A new technique isolates neuronal activity during memory consolidation

22.06.2017 | Life Sciences

Plant inspiration could lead to flexible electronics

22.06.2017 | Materials Sciences

A rhodium-based catalyst for making organosilicon using less precious metal

22.06.2017 | Materials Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>