In language and arts depression is associated with darkness and grey and black colours. Everything looks grey when people feel blue.
There might be an empirical truth behind these idioms according to the findings of a research group at the University Hospital Freiburg in Germany, who combined neuropsychiatric and ophthalmologic investigations.
In earlier work they were able to demonstrate that depressed people do have difficulties with detecting black-and-white contrast differences.
In another study published in 2010 they focused on the response of the retina in depressed and healthy humans to varying black-and-white contrasts. Measuring the pattern of an electroretinogram, which is a kind of electrocardiogram (ECG) of the eye, they found dramatic reductions in response amplitudes of the eyes of depressed patients.
The signal was so strong that it was able to distinguish most depressed patients on a single case basis from healthy control subjects when looking at the electrophysiological measurement.
In the latest study just published in the renowned British Journal of Psychiatry (http://bjp.rcpsych.org/content/201/2/151.full) they now report that the abnormal retinal signal normalised following remission of depression. Therefore the objectively measurable retinal contrast gain might prove to be an objective state marker of depression.
Should these findings be replicated in further studies, this method could turn out to be a valuable tool to objectively measure the subjective state of depression. This could have far reaching implications for research as well as clinical diagnosis and therapy of depression.Kontakt:
Doreen Winkler | idw
Antibiotic effective against drug-resistant bacteria in pediatric skin infections
17.02.2017 | University of California - San Diego
Tiny magnetic implant offers new drug delivery method
14.02.2017 | University of British Columbia
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
17.02.2017 | Medical Engineering
17.02.2017 | Medical Engineering
17.02.2017 | Health and Medicine