Chronic use of prescription painkillers, also known as opioids, among obese patients prior to bariatric surgery continues after surgery, according to a new Kaiser Permanente study published today in the Journal of the American Medical Association.
Researchers examined the electronic medical records of 11,719 obese patients who underwent bariatric surgery between 2005-2009 at one of 10 U.S. sites in the Scalable Partnering Network. Participating patients were evaluated one year before and one year after surgery. Seventy-seven percent of the obese patients who exhibited chronic opioid use prior to surgery continued to use these medications chronically one year after their procedure. Chronic opioid use among these patients also increased by 13 percent the first year after surgery.
"Obese patients are often more sensitive to pain and tend to be prescribed increasing opioid doses in order to manage that pain," said lead study author Marsha A. Raebel, PharmD, a senior investigator at Kaiser Permanente's Institute for Health Research.
In the year prior to their surgical procedures, 56 percent of the patients in this study reported no opioid use for pain management, 36 percent used some opioids and 8 percent used opioids on a chronic basis. Chronic opioid use was defined as having 10 or more prescriptions over at least 90 days or at least a 120-day total supply of medication sometime in the year prior to surgery. Some opioid use was defined as one to nine prescriptions over 90 days or less than a 120-day supply.
"There are limited options for pain management available to bariatric surgery patients because non-steroidal, anti-inflammatory medications increase the risk of ulcers, particularly after bariatric surgery," said Dr. Raebel. "Given the increasing chronic usage rate reported in this study, it's clear that the medical community needs to develop better pain management programs for patients who use opioids long-term following bariatric surgery."
More than 200,000 bariatric surgeries were performed in the U.S. in 2012 and prescription painkiller usage has exploded at the same time. According to the medical journal Pain, 4.3 million adults use opioid medications on a regular basis. The most commonly used prescription opioids are hydrocodone, oxycodone and morphine. Long-term opioid use can lead to many health issues, the most serious being addiction and fatal overdoses.
Kaiser Permanente is committed to furthering understanding of chronic opioid use. Earlier in 2013, a Kaiser Permanente study found that regularly taking opioids increases a man's risk of erectile dysfunction.
Kaiser Permanente can conduct transformational health research like this in part because it has the largest private patient-centered electronic health record system in the world. The organization's electronic health record system, Kaiser Permanente HealthConnect®, securely connects 9.1 million patients to 17,000 physicians in 611 medical offices and 37 hospitals. It also connects Kaiser Permanente's research scientists to one of the most extensive collections of longitudinal medical data available, facilitating studies and important medical discoveries that shape the future of health care delivery for patients and the medical community.
Additional study authors include: Sophia R. Newcomer, MPH, Liza M. Reifler, MPH, and Elizabeth A. Bayliss, MD, MSPH, of the Kaiser Permanente Institute for Health Research; Denise Boudreau, PhD, of Group Health Research Institute, Seattle; Thomas E. Elliott, MD, of the Essentia Institute of Rural Health, Duluth, Minn.; Lynn DeBar, PhD, of the Kaiser Permanente Center for Health Research, Portland, Ore.; Ameena Ahmed, MD, MPH, and David Fisher, MD, of the Permanente Medical Group, San Francisco; Pamala A. Pawloski, PharmD, of the HealthPartners Institute for Education and Research, Minneapolis; and W. Troy Donahoo, MD, of the Colorado Permanente Medical Group, Denver.About the Kaiser Permanente Colorado Institute for Health Research
Team discovers how bacteria exploit a chink in the body's armor
20.01.2017 | University of Illinois at Urbana-Champaign
Rabies viruses reveal wiring in transparent brains
19.01.2017 | Rheinische Friedrich-Wilhelms-Universität Bonn
An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...
Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...
Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.
While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...
Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales
Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...
Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.
As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...
19.01.2017 | Event News
10.01.2017 | Event News
09.01.2017 | Event News
20.01.2017 | Awards Funding
20.01.2017 | Materials Sciences
20.01.2017 | Life Sciences