For this, it is essential to provide tests that allow early detection of cancer without the need of a tissue sample, and thus drastically improve the prognosis of the patients and their chance of a cure. Currently established cancer diagnostics either identify the disease too late or are unreliable, resulting in false positives, which can unsettle patients.
For instance, measuring PSA-levels for prostate cancer detection and mammographies for breast cancer prevention can provide false positive results without acute malignancies being found. Additionally, currently no blood test is available for oral cancer.
A novel blood test for the detection of cancer has been clinically assessed in a collaborative study between the university hospital Tuebingen, the German Cancer Research Center in Heidelberg, and the Clemenshospital of the university hospital muenster. This blood test utilizes the immune system; specifically the activity of macrophages, a type of white blood cell that scavenges tumor cells.
Using laser-based detection methods of tumor material within these scavenger cells, also known as EDIM (epitope detection in monocytes)-technology, it is now possible to discover the presence of tumor cells in small blood samples. This has allowed the early detection of oral, prostate, and breast cancer as well as relapses in patients by the EDIM-technology. Thus, this technology is also suitable for monitoring therapeutic efficacy. The results of this study represent an important hallmark in cancer detection, driven by the improved accuracy of the EDIM-blood test compared to previously established test methodologies.
publicationA biomarker based detection and characterization of carcinomas exploiting two fundamental biophysical mechanisms in mammalian cells
Dr. Ellen Katz | idw
Using bacterial 'fight clubs' to find new drugs
30.06.2015 | Vanderbilt University
Patients with recurrent depression have smaller hippocampi
30.06.2015 | University of Sydney
New technique combines electron microscopy and synchrotron X-rays to track chemical reactions under real operating conditions
A new technique pioneered at the U.S. Department of Energy's Brookhaven National Laboratory reveals atomic-scale changes during catalytic reactions in real...
Think of an object made of iron: An I-beam, a car frame, a nail. Now imagine that half of the iron in that object owes its existence to bacteria living two and a half billion years ago.
Think of an object made of iron: An I-beam, a car frame, a nail. Now imagine that half of the iron in that object owes its existence to bacteria living two and...
A team of scientists including PhD student Friedrich Schuler from the Laboratory of MEMS Applications at the Department of Microsystems Engineering (IMTEK) of...
The three-year clinical trial results of the retinal implant popularly known as the "bionic eye," have proven the long-term efficacy, safety and reliability of...
On June 23, the second Sentinel mission was launched from the space mission launch center in Kourou. A critical component of Aachen is on board. Researchers at the Fraunhofer Institute for Laser Technology ILT and Tesat-Spacecom have jointly developed the know-how for space-qualified laser components. For the Sentinel mission the diode laser pump module of the Laser Communication Terminal LCT was planned and constructed in Aachen in cooperation with the manufacturer of the LCT, Tesat-Spacecom, and the Ferdinand Braun Institute.
After eight years of preparation, in the early morning of June 23 the time had come: in Kourou in French Guiana, the European Space Agency launched the...
25.06.2015 | Event News
16.06.2015 | Event News
11.06.2015 | Event News
30.06.2015 | Physics and Astronomy
30.06.2015 | Physics and Astronomy
30.06.2015 | Materials Sciences