A minimally invasive procedure known as endovascular repair used for abdominal aortic aneurysms has a low rate of complications, even in high-risk patients such as those with kidney, heart or lung problems, a Mayo Clinic study shows.
Researchers found that even when aneurysms ruptured, endovascular repair had lower mortality rates than open-abdominal surgery, the other treatment option. The findings are being presented at the Midwestern Vascular Surgical Society Annual Meeting, Sept. 6-8, in Milwaukee, Wis.
An abdominal aortic aneurysm is a weakened and bulging area in the lower part of the aorta, the major blood vessel that supplies blood to the body. A ruptured abdominal aortic aneurysm can cause life-threatening bleeding. In endovascular surgery, physicians attach a synthetic graft to the end of a thin tube, or catheter, inserted through a groin artery and threaded up into the aorta. The graft is placed at the site of the aneurysm and fastened in place, reinforcing the aorta to prevent rupture.
Recovery time typically includes a day in the hospital and one or two weeks of rest at home, compared with five to seven days in the hospital and four to six weeks at home after open-abdominal surgery.
"During the last decade or so we have performed over 1,000 endovascular repairs of abdominal aortic aneurysms that included patients with no symptoms at all and patients who presented with a life-threatening rupture. We found that endovascular repair results in a low mortality and a low rate of complications, and that was very rewarding," says lead author Peter Gloviczki, M.D., a Mayo Clinic vascular and endovascular surgeon.
Using a Mayo Clinic aortic registry, researchers analyzed data from 1,008 consecutive patients receiving endovascular repair between 1997 and 2011.
Abdominal aortic aneurysms are more common in men than in women, and that was reflected in the cases studied: 133 were women and 875 were men. They ranged in age from 49 to 99, with a mean age of 76. Thirty-day mortality after repair of non-ruptured aneurysms was 0.2 percent in good-risk and 2.2 percent in high-risk patients. The five-year survival rate was 72 percent for good-risk patients and 51 percent for those at high risk; three-fourths of those in either group were free from early and late complications, which can include post-procedure bleeding, blood clots or problems with the repair.
Age and high surgical risk were associated with complications and early and all-cause death. Women were likelier than men to have complications, but weren't at higher risk of death.
Abdominal aortic aneurysms often develop without symptoms. Men with a family history of aneurysms should be screened at age 55 with abdominal ultrasounds. Smokers, people with high cholesterol or high blood pressure, and women with a family history of aneurysms should be screened at 65, says Dr. Gloviczki, the Joe M. and Ruth Roberts Professor of Surgery at Mayo Clinic and president of the Society for Vascular Surgery.
MULTIMEDIA ALERT: An illustration and video interview with Dr. Gloviczki are available for journalists to download on the Mayo Clinic News Network.
About Mayo Clinic
Mayo Clinic is a nonprofit worldwide leader in medical care, research and education for people from all walks of life. For more information, visit http://www.mayoclinic.org/about and www.mayoclinic.org/news.Contact:
Sharon Theimer | EurekAlert!
Gentle sensors for diagnosing brain disorders
29.09.2016 | King Abdullah University of Science and Technology
New imaging technique in Alzheimer’s disease - opens up possibilities for new drug development
28.09.2016 | Lund University
Physicists from the University of Würzburg have designed a light source that emits photon pairs. Two-photon sources are particularly well suited for tap-proof data encryption. The experiment's key ingredients: a semiconductor crystal and some sticky tape.
So-called monolayers are at the heart of the research activities. These "super materials" (as the prestigious science magazine "Nature" puts it) have been...
Ultrafast lasers have introduced new possibilities in engraving ultrafine structures, and scientists are now also investigating how to use them to etch microstructures into thin glass. There are possible applications in analytics (lab on a chip) and especially in electronics and the consumer sector, where great interest has been shown.
This new method was born of a surprising phenomenon: irradiating glass in a particular way with an ultrafast laser has the effect of making the glass up to a...
Terahertz excitation of selected crystal vibrations leads to an effective magnetic field that drives coherent spin motion
Controlling functional properties by light is one of the grand goals in modern condensed matter physics and materials science. A new study now demonstrates how...
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
28.10.2016 | Power and Electrical Engineering
28.10.2016 | Physics and Astronomy
28.10.2016 | Life Sciences