Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Barrow study identifies new way to biopsy brain tumors in real time

13.11.2009
New microscope is expected to improve the accuracy of intraoperative diagnostics

A new miniature, hand-held microscope may allow more precise removal of brain tumors and an easier recognition of tumor locations during surgery.

Neurosurgeons at Barrow Neurological Institute at St. Joseph's Hospital and Medical Center are using the new miniature laser confocal microscope to view brain tumor regions during surgery and obtain digital images of the tumor and brain tissue. This was not previously possible without taking biopsies of the tissue.

The microscope is used to image the tissue after a fluorescent drug is injected into the patient and travels into the tumor. The first application of the technology in the research lab at Barrow showed that it was possible to distinguish cancer cells and the margin of the brain tumor without taking a biopsy. Barrow researchers also discovered that it was possible to obtain a digital video of the brain tumor to show blood flowing through the abnormal vessels of the tumor and the transition from normal to abnormal brain tissue.

Typically, intraoperative diagnosis is performed by obtaining several specimens from within a brain tumor using biopsy forceps and cutting, freezing and staining the specimen for examination under the microscope. The traditional analysis is limited by sampling error and by mechanical tissue damage from the biopsy forceps, slowing operative workflow by 30 to 40 minutes.

The new microscope can overcome these limitations by helping to visualize the cellular and tissue features of a tumor in real-time. As in the study, the probe can be moved over the entire visible extent of a tumor, guiding the neurosurgeon to hypercellular or aggressive areas that are likely to generate high-yield biopsies.

"As neuropathologists become familiar with the new confocal microscopic appearance of various tumor types and grades, the traditional intraoperative diagnosis may be replaced by the real-time analysis of confocal images by the new microscope," says Mark Preul, MD, Newsome Chair of Neurosurgery Research at Barrow. These images could be analyzed remotely, improving the accuracy of intraoperative diagnosis.

This study was presented at the Annual Meeting of the American Association of Neurological Surgeons in San Diego and was recently published in the Journal of Neurosurgery.

Carmelle Malkovich | EurekAlert!
Further information:
http://www.chw.edu

More articles from Medical Engineering:

nachricht Heart examinations: Miniature particle accelerator saves on contrast agents
27.02.2017 | Technische Universität München

nachricht Novel breast tomosynthesis technique reduces screening recall rate
21.02.2017 | Radiological Society of North America

All articles from Medical Engineering >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Safe glide at total engine failure with ELA-inside

On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded after a glide flight with an Airbus A320 in ditching on the Hudson River. All 155 people on board were saved.

On January 15, 2009, Chesley B. Sullenberger was celebrated world-wide: after the two engines had failed due to bird strike, he and his flight crew succeeded...

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

New pop-up strategy inspired by cuts, not folds

27.02.2017 | Materials Sciences

Sandia uses confined nanoparticles to improve hydrogen storage materials performance

27.02.2017 | Interdisciplinary Research

Decoding the genome's cryptic language

27.02.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>