UC Irvine biologists help sequence Hydra genome
Survey finds genes linked to Huntington's, Alzheimer's disease
UC Irvine researchers have played a leading role in the genome sequencing of Hydra, a freshwater polyp that has been a staple of biological research for 300 years.
In the March 14 online version of Nature, UCI biologists Robert Steele and Hans Bode, along with nine other UCI scientists and an international team of researchers, describe the genome sequence of an organism that continues to advance research on regeneration, stem cells and patterning.
The team discovered Hydra to have about the same number of genes as humans, sharing many of the same ones. Surprisingly, they also found genes linked with Huntington's disease and with the beta-amyloid plaque formation seen in Alzheimer's disease – two areas in which UCI has traditionally strong research programs – suggesting the possible use of Hydra as a research model for these two diseases.
"Having the Hydra genome sequenced also enhances our ability to use it to learn more about the basic biology of stem cells, which are showing great promise for new treatments for a host of injuries and diseases," said Steele, associate professor and interim chair in biological chemistry.
Started in 2004, the Hydra project is the first genome sequencing effort in which UCI scientists have played a major role. The sequencing was carried out at the J. Craig Venter Institute and was funded by the National Human Genome Research Institute.
Tom Vasich | EurekAlert!
The most recent press releases about innovation >>>
Die letzten 5 Focus-News des innovations-reports im Überblick:
A newly developed laser technology has enabled physicists in the Laboratory for Attosecond Physics (jointly run by LMU Munich and the Max Planck Institute of Quantum Optics) to generate attosecond bursts of high-energy photons of unprecedented intensity. This has made it possible to observe the interaction of multiple photons in a single such pulse with electrons in the inner orbital shell of an atom.
In order to observe the ultrafast electron motion in the inner shells of atoms with short light pulses, the pulses must not only be ultrashort, but very...
A group of researchers led by Andrea Cavalleri at the Max Planck Institute for Structure and Dynamics of Matter (MPSD) in Hamburg has demonstrated a new method enabling precise measurements of the interatomic forces that hold crystalline solids together. The paper Probing the Interatomic Potential of Solids by Strong-Field Nonlinear Phononics, published online in Nature, explains how a terahertz-frequency laser pulse can drive very large deformations of the crystal.
By measuring the highly unusual atomic trajectories under extreme electromagnetic transients, the MPSD group could reconstruct how rigid the atomic bonds are...
International research team makes important step on the path to solving certification problems
Quantum computers may one day solve algorithmic problems which even the biggest supercomputers today can’t manage. But how do you test a quantum computer to...
For the first time, a team of researchers at the Max-Planck Institute (MPI) for Polymer Research in Mainz, Germany, has succeeded in making an integrated circuit (IC) from just a monolayer of a semiconducting polymer via a bottom-up, self-assembly approach.
In the self-assembly process, the semiconducting polymer arranges itself into an ordered monolayer in a transistor. The transistors are binary switches used...
Breakthrough provides a new concept of the design of molecular motors, sensors and electricity generators at nanoscale
Researchers from the Institute of Organic Chemistry and Biochemistry of the CAS (IOCB Prague), Institute of Physics of the CAS (IP CAS) and Palacký University...