Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Tomato genes produce promising results against brain tumours

30.03.2010
Tomato genes could be used as a future treatment in gene therapy, according to new research results from Lund University.

Jure Piskur is a Professor at the Department of Biology, Lund University.

Together with colleagues from Stockholm, Copenhagen and Lund, he has recently published research results on a tomato gene that it seems could be of value in future treatment of brain tumours. The results are reported in the journal Neuro-Oncology.

Research on gene therapy has been underway for a long time and last autumn the first gene therapy treatment was launched onto the market, by Ark Therapeutics from Kuopio in Finland.

The idea of gene therapy is to introduce an alien gene into a patient's cancer cells. In combination with a specific drug, the introduced gene can cause the cancer cells to die. The tumour does not disappear, but the hope is that the disease can be halted for a couple of years.

"Our research results on the tomato gene show a superior alternative to the main ingredient that they have started using in Finland and we have now begun cooperating with the researchers in Kuopio", says Jure Piskur.

It certainly sounds incredible that it could be possible to use a tomato plant in cancer treatment. Jure Piskur explains that it is a matter of 'suicide genes', which can cause cells to die.

In the tomato the gene's actual task is to produce small building blocks for the plant's genetic make-up, but in combination with the drug AZT the tomato gene appears to kill the cancer cells. AZT is a drug that was first developed in the fight against HIV.

Professor Piskur came into contact with cancer research by chance. He is a researcher in molecular evolution and his interests include how enzymes have developed over millions of years. Enzymes are proteins that set off or speed up different chemical reactions in the body.

Jure Piskur has studied enzymes in a wide range of different organisms, from bacteria to animals. The tomato gene in question codes for an enzyme called thymidine kinase.

For more information: Jure Piskur, Department of Biology, tel. +46 (0)46 222 83 73, Jure.Piskur@cob.lu.se

Pressofficer Lena Björk Blixt; +46-46 222 7186; Lena.Bjork_Blixt@kanslin.lu.se

Lena Björk | idw
Further information:
http://www.ncbi.nlm.nih.gov/pubmed/20154339
http://www.lu.se

More articles from Life Sciences:

nachricht Warming ponds could accelerate climate change
21.02.2017 | University of Exeter

nachricht An alternative to opioids? Compound from marine snail is potent pain reliever
21.02.2017 | University of Utah

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Impacts of mass coral die-off on Indian Ocean reefs revealed

21.02.2017 | Earth Sciences

Novel breast tomosynthesis technique reduces screening recall rate

21.02.2017 | Medical Engineering

Use your Voice – and Smart Homes will “LISTEN”

21.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>