Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


The secretive immune system of the salmon

During his doctoral thesis, Erlend Haugarvoll discovered new aspects of the salmon immune system. His research looked at the immune cells in the gills of salmon and at immune responses to vaccination. A special type of tissue, rich in immune cells, was found in the gills, and new properties of immune cells that produce brown pigment were discovered.

Successful salmon farming in Norway and other countries depends on the use of vaccination. Vaccination gives salmon good protection against several diseases, but has serious side-effects.

Inflammatory reactions at the injection site can lead to reduced growth rate, reduced meat quality and deformities, raising both economical and ethical around current vaccination regimes. In order to improve resistance to disease in salmon, it is important to find alternative vaccination methods and to acquire more knowledge of how salmon react to vaccination.

Haugarvoll and his colleagues discovered in salmon gill a tissue extremely rich in immune cells. Salmon gills have extremely thin mucous membranes, and they absorb oxygen from the water while keeping out potentially damaging microbes. The fish are therefore dependent on good disease resistance in this organ. The discoveries made by Haugarvoll may prove extremely useful when new vaccines, free from damaging side effects, are developed.

Some fish immune cells contain the pigment melanin, which is the same substance that darkens the skin of people and animals. These cells have been called melanomacrophages and it has been assumed they play a central role in the defence of fish against microbes. The work of Haugarvoll and his associates showed that melanomacrophages in salmon produce their own melanin. There is also reason to believe that this pigment has an important role in the salmon defence system.

Vaccination is a very effective way of protecting animals against infectious disease and has nearly removed the need for antibiotics in Norwegian salmon farming. In his doctorate, Haugarvoll investigated currently unknown sides of fish immune defence, and his work gives hope that vaccines may be developed that can be applied externally.

Cand. med. vet. Erlend Haugarvoll defended his thesis for the degree of Doctor of Philosophy, entitled " Novel leukocyte localisations and characteristics in the Atlantic salmon", on December 16, 2008, at the Norwegian School of Veterinary Science.

Magnhild Jenssen | alfa
Further information:

More articles from Life Sciences:

nachricht Make way for the mini flying machines
21.03.2018 | American Chemical Society

nachricht New 4-D printer could reshape the world we live in
21.03.2018 | American Chemical Society

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Researchers at Fraunhofer monitor re-entry of Chinese space station Tiangong-1

In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.

Following the loss of radio contact with Tiangong-1 in 2016 and due to the low orbital height, it is now inevitable that the Chinese space station will...

Im Focus: Alliance „OLED Licht Forum“ – Key partner for OLED lighting solutions

Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.

They are united in their passion for OLED (organic light emitting diodes) lighting with all of its unique facets and application possibilities. Thus experts in...

Im Focus: Mars' oceans formed early, possibly aided by massive volcanic eruptions

Oceans formed before Tharsis and evolved together, shaping climate history of Mars

A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...

Im Focus: Tiny implants for cells are functional in vivo

For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of live zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published in Nature Communications.

In the cells of higher organisms, organelles such as the nucleus or mitochondria perform a range of complex functions necessary for life. In the networks of...

Im Focus: Locomotion control with photopigments

Researchers from Göttingen University discover additional function of opsins

Animal photoreceptors capture light with photopigments. Researchers from the University of Göttingen have now discovered that these photopigments fulfill an...

All Focus news of the innovation-report >>>



Industry & Economy
Event News

Virtual reality conference comes to Reutlingen

19.03.2018 | Event News

Ultrafast Wireless and Chip Design at the DATE Conference in Dresden

16.03.2018 | Event News

International Tinnitus Conference of the Tinnitus Research Initiative in Regensburg

13.03.2018 | Event News

Latest News

TRAPPIST-1 planets provide clues to the nature of habitable worlds

21.03.2018 | Physics and Astronomy

The search for dark matter widens

21.03.2018 | Materials Sciences

Natural enemies reduce pesticide use

21.03.2018 | Life Sciences

Science & Research
Overview of more VideoLinks >>>