Successful salmon farming in Norway and other countries depends on the use of vaccination. Vaccination gives salmon good protection against several diseases, but has serious side-effects.
Inflammatory reactions at the injection site can lead to reduced growth rate, reduced meat quality and deformities, raising both economical and ethical around current vaccination regimes. In order to improve resistance to disease in salmon, it is important to find alternative vaccination methods and to acquire more knowledge of how salmon react to vaccination.
Haugarvoll and his colleagues discovered in salmon gill a tissue extremely rich in immune cells. Salmon gills have extremely thin mucous membranes, and they absorb oxygen from the water while keeping out potentially damaging microbes. The fish are therefore dependent on good disease resistance in this organ. The discoveries made by Haugarvoll may prove extremely useful when new vaccines, free from damaging side effects, are developed.
Some fish immune cells contain the pigment melanin, which is the same substance that darkens the skin of people and animals. These cells have been called melanomacrophages and it has been assumed they play a central role in the defence of fish against microbes. The work of Haugarvoll and his associates showed that melanomacrophages in salmon produce their own melanin. There is also reason to believe that this pigment has an important role in the salmon defence system.
Vaccination is a very effective way of protecting animals against infectious disease and has nearly removed the need for antibiotics in Norwegian salmon farming. In his doctorate, Haugarvoll investigated currently unknown sides of fish immune defence, and his work gives hope that vaccines may be developed that can be applied externally.
Cand. med. vet. Erlend Haugarvoll defended his thesis for the degree of Doctor of Philosophy, entitled " Novel leukocyte localisations and characteristics in the Atlantic salmon", on December 16, 2008, at the Norwegian School of Veterinary Science.
Magnhild Jenssen | alfa
Single-stranded DNA and RNA origami go live
15.12.2017 | Wyss Institute for Biologically Inspired Engineering at Harvard
New antbird species discovered in Peru by LSU ornithologists
15.12.2017 | Louisiana State University
DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
11.12.2017 | Event News
08.12.2017 | Event News
07.12.2017 | Event News
15.12.2017 | Power and Electrical Engineering
15.12.2017 | Materials Sciences
15.12.2017 | Life Sciences