Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Roads pave the way for the spread of superbugs

30.09.2011
Antibiotic resistant E. coli was much more prevalent in villages situated along roads than in rural villages located away from roads, which suggests that roads play a major role in the spread or containment of antibiotic resistant bacteria, commonly called superbugs, a new study finds.

Many studies on various infectious diseases have shown that roads impact the spread of disease, however this is the first known study to show that roads also impact the spread of antibiotic resistant bacteria, said Joe Eisenberg, co-author and professor at the University of Michigan School of Public Health.

Researchers at the U-M SPH and colleagues from Universidad San Francisco de Quito, and Trinity College studied a region in northwest Ecuador for five years, focusing on antibiotic resistant E. coli and the common antibiotic paring of ampicillin and sulfamethoxazole.

"Our results show it's not just the individual's antibiotic use that affects antibiotic resistance," Eisenberg said. "Other important factors that affect the spread of antibiotic resistance are the rates at which people introduce new strains due to movement in and out of the region, as well as poor water quality and sanitation that allow for the transmission of antibiotic resistant strains." Both of these factors are influenced by the presence of the roads.

"We focus so much on the individual, and if they do or don't take antibiotics, but we're learning more and more that there's a broader environmental and social context in which antibiotic resistance happens," Eisenberg said.

While increased antibiotic use over long periods of time can increase antibiotic resistance with bacteria such as E. coli, when antibiotics are taken for much shorter periods of time, they have a different effect on bacteria.

For those bacteria, taking antibiotics amplifies antibiotic resistant bacteria that already exists in the individual, by killing the non-resistant E. coli., which encourages the superbug strains to multiply and take over in the gut.

This superbug E. coli becomes the dominant strain, thus increasing the likelihood that it is transmitted from one person to another. A transmission event can occur when, for example, an infected person contaminates food they are preparing or a water source they are bathing in and an uninfected person subsequently is exposed to the contaminated food or water source. Thus, the road influences health not only through providing more access to antibiotics, but also through creating different levels of water sanitation and hygiene.

"If we want to think about how we deal with antibiotic resistance we have got to think about the broader environmental forces that cause the spread of antibiotic resistance, in addition to how doctors prescribe antibiotics to individuals," Eisenberg said.

The paper, "In-roads to the spread of antibiotic resistance: regional patterns of microbial transmission in northern coastal Ecuador," appears this month in the Journal of the Royal Society, Interface.

For more on Eisenberg: http://www.sph.umich.edu/iscr/faculty/profile.cfm?uniqname=jnse

For more on Department of Epidemiology: http://www.sph.umich.edu/epid/

The University of Michigan School of Public Health has been promoting health and preventing disease since 1941, and is ranked among the top public health schools in the nation. Whether making new discoveries in the lab or researching and educating in the field, our faculty, students, and alumni are deployed around the globe to promote and protect our health http://www.sph.umich.edu/

Laura Bailey | EurekAlert!
Further information:
http://www.umich.edu

More articles from Life Sciences:

nachricht Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery
20.01.2017 | GSI Helmholtzzentrum für Schwerionenforschung GmbH

nachricht Seeking structure with metagenome sequences
20.01.2017 | DOE/Joint Genome Institute

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Helmholtz International Fellow Award for Sarah Amalia Teichmann

20.01.2017 | Awards Funding

An innovative high-performance material: biofibers made from green lacewing silk

20.01.2017 | Materials Sciences

Ion treatments for cardiac arrhythmia — Non-invasive alternative to catheter-based surgery

20.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>