It is believed to be the first time that chemometric modeling of spectral data has been used to determine the time elapse after death of skeletal remains. In laboratory tests using this method, Baylor researchers found an error rate of only four to nine days for bones that were up to 90-days old.
“In perfect conditions in the laboratory, the method looks very encouraging,” said Dr. Kenneth Busch, professor of chemistry and co-director of the Center for Analytical Spectroscopy at Baylor and a lead investigator on the project. “Once a regression model is built from spectral data, you could find out the age of the bones in a matter of minutes, rather than taking hours or days.”
Once skeletization occurs, few techniques exist to determine the post-mortem interval of remains in a timely matter. In regions with high heat and humidity, excarnation can occur relatively quickly. Following death, bones lose water and the proteins begin to decompose to amino acids. Baylor researchers were able to follow these changes spectroscopically and correlate the data with the post-mortem interval by using regression modeling.
The Baylor researchers sampled 28 different pig bones that were up to 90-days old and used diffuse reflectance spectroscopy to try to date the skeletal remains. Busch said diffuse reflectance spectroscopy was used because it is non-destructive and is sensitive to protein and moisture. The bones were subjected to different light beams and the researchers found that the diffuse reflectance decreased as time moved on. The spectral data was then correlated with the known ages of the bones.
The researchers found the diffuse reflectance spectra of bones seemed to show some non-linearity in respect to changes with time. They decided to segment the data and divide it into three sets and make models for each. They found that by using the segmented approach, it would cut the prediction error substantially compared with the original 90-day model.
However this created a problem – which model should be used for an unknown bone sample? They found classifying the bones based on a discriminant analysis model followed by a segmented regression model gave the best results.
The research paper outlining the technique and results was presented at the annual meeting of the Federation of Analytical Chemistry and Spectroscopy Societies.
Chartered in 1845 by the Republic of Texas, Baylor University is the oldest, continually operating university in the state. Baylor’s 735-acre campus in Waco, Texas, is home to more than 14,500 students from all 50 states and 70 countries, who can choose from more than 140 undergraduate and 100 graduate programs through 11 academic units. Baylor, a private Christian university and a nationally ranked liberal arts institution, is classified by the Carnegie Foundation for the Advancement of Teaching as a research university with “high research activity.” This blends with Baylor’s international reputation for educational excellence built upon the faculty’s commitment to teaching, scholarship and interdisciplinary research to produce outstanding graduates.
Matt Pene | Newswise Science News
Novel mechanisms of action discovered for the skin cancer medication Imiquimod
21.10.2016 | Technische Universität München
Second research flight into zero gravity
21.10.2016 | Universität Zürich
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
21.10.2016 | Health and Medicine
21.10.2016 | Information Technology
21.10.2016 | Materials Sciences