Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

First Report on Bioaccumulation and Processing of Antibacterial Ingredient TCC in Fish

01.04.2011
In the first report on the uptake and internal processing of triclocarban (TCC) in fish, scientists today reported strong evidence that TCC — an antibacterial ingredient in some soaps and the source of environmental health concerns because of its potential endocrine-disrupting effects — has a “strong” tendency to bioaccumulate in fish. They presented the findings here today at the 241st National Meeting & Exposition of the American Chemical Society.

Bioaccumulation occurs when fish or other organisms take in a substance faster than their bodies can break it down and eliminate it. If a substance can be bioaccumulated, even minute and seemingly harmless amounts in the water can build up to toxic amounts inside the body.

Ida Flores, who presented the results, pointed out that all existing evidence indicates that TCC does not bioaccumulate in humans and certain other mammals. The human body quickly breaks down, or metabolizes TCC, changing it into other substances that exit the body in urine and feces.

The new study, however, suggests that the situation may be different for fish. They encounter TCC, found mainly in bar soaps, in water that washes down the drain and flows out of sewage treatment facilities into lakes and streams with a small amount of the TCC intact.

Along with a related ingredient called triclosan, TCC has been the source of controversy in recent years. Studies suggested that TCC and triclosan are no better than ordinary soap in preventing the spread of disease, and showed that the two substances have the potential to disrupt the activity of reproductive hormones.

“Due to its widespread usage, TCC is present in small amounts in 60 percent of all rivers and streams in the United States,” said study leader Ida Flores, of the University of California-Davis. “Fish are commonly exposed to TCC, even though much of it is eliminated by wastewater treatment plants.” Despite that widespread distribution in the environment, Flores and colleagues were surprised that only a few studies had investigated TCC’s role in aquatic ecosystems.

“Some of those showed that TCC does accumulate in the environment, and this compelled us to look at the environmental effects of TCC on fish — not simply seeing how it accumulates in fish but also how it is processed and eliminated,” Flores explained.

To find out, they exposed one-week-old larvae of medaka fish, an approach often used in research of endocrine disrupting effects to amounts of TCC similar to those found in natural waterways, and analyzed how the fish metabolized TCC.

“The fish quickly accumulated TCC,” Flores said. “The levels of the TCC in the fish soon after exposure were about 1,000 times higher than the concentration in the water. To the best of our knowledge, this is the first report of uptake and metabolism of TCC in fish species. We found evidence of strong accumulation and also got details on exactly how TCC is metabolized in these animals.”

Flores explained that details of TCC’s metabolism are important because they play a key role in understanding the health and environmental effects of TCC.

“Unmetabolized compounds, such as dioxins, can’t be excreted from the body,” Flores noted. “Those that can be metabolized pose decreased health risks because they can be excreted. Our major concern is accumulation of TCC in the environment and impacts on ecology by its potential endocrine disrupting effects.”

The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 163,000 members, ACS is the world’s largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

Michael Bernstein | Newswise Science News
Further information:
http://www.acs.org

More articles from Life Sciences:

nachricht Closing in on advanced prostate cancer
13.12.2017 | Institute for Research in Biomedicine (IRB Barcelona)

nachricht Visualizing single molecules in whole cells with a new spin
13.12.2017 | Wyss Institute for Biologically Inspired Engineering at Harvard

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Long-lived storage of a photonic qubit for worldwide teleportation

MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.

Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...

Im Focus: Electromagnetic water cloak eliminates drag and wake

Detailed calculations show water cloaks are feasible with today's technology

Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...

Im Focus: Scientists channel graphene to understand filtration and ion transport into cells

Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.

To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...

Im Focus: Towards data storage at the single molecule level

The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.

Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...

Im Focus: Successful Mechanical Testing of Nanowires

With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong

Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

AKL’18: The opportunities and challenges of digitalization in the laser industry

07.12.2017 | Event News

 
Latest News

A whole-body approach to understanding chemosensory cells

13.12.2017 | Health and Medicine

Water without windows: Capturing water vapor inside an electron microscope

13.12.2017 | Physics and Astronomy

Cellular Self-Digestion Process Triggers Autoimmune Disease

13.12.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>