Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:


First Report on Bioaccumulation and Processing of Antibacterial Ingredient TCC in Fish

In the first report on the uptake and internal processing of triclocarban (TCC) in fish, scientists today reported strong evidence that TCC — an antibacterial ingredient in some soaps and the source of environmental health concerns because of its potential endocrine-disrupting effects — has a “strong” tendency to bioaccumulate in fish. They presented the findings here today at the 241st National Meeting & Exposition of the American Chemical Society.

Bioaccumulation occurs when fish or other organisms take in a substance faster than their bodies can break it down and eliminate it. If a substance can be bioaccumulated, even minute and seemingly harmless amounts in the water can build up to toxic amounts inside the body.

Ida Flores, who presented the results, pointed out that all existing evidence indicates that TCC does not bioaccumulate in humans and certain other mammals. The human body quickly breaks down, or metabolizes TCC, changing it into other substances that exit the body in urine and feces.

The new study, however, suggests that the situation may be different for fish. They encounter TCC, found mainly in bar soaps, in water that washes down the drain and flows out of sewage treatment facilities into lakes and streams with a small amount of the TCC intact.

Along with a related ingredient called triclosan, TCC has been the source of controversy in recent years. Studies suggested that TCC and triclosan are no better than ordinary soap in preventing the spread of disease, and showed that the two substances have the potential to disrupt the activity of reproductive hormones.

“Due to its widespread usage, TCC is present in small amounts in 60 percent of all rivers and streams in the United States,” said study leader Ida Flores, of the University of California-Davis. “Fish are commonly exposed to TCC, even though much of it is eliminated by wastewater treatment plants.” Despite that widespread distribution in the environment, Flores and colleagues were surprised that only a few studies had investigated TCC’s role in aquatic ecosystems.

“Some of those showed that TCC does accumulate in the environment, and this compelled us to look at the environmental effects of TCC on fish — not simply seeing how it accumulates in fish but also how it is processed and eliminated,” Flores explained.

To find out, they exposed one-week-old larvae of medaka fish, an approach often used in research of endocrine disrupting effects to amounts of TCC similar to those found in natural waterways, and analyzed how the fish metabolized TCC.

“The fish quickly accumulated TCC,” Flores said. “The levels of the TCC in the fish soon after exposure were about 1,000 times higher than the concentration in the water. To the best of our knowledge, this is the first report of uptake and metabolism of TCC in fish species. We found evidence of strong accumulation and also got details on exactly how TCC is metabolized in these animals.”

Flores explained that details of TCC’s metabolism are important because they play a key role in understanding the health and environmental effects of TCC.

“Unmetabolized compounds, such as dioxins, can’t be excreted from the body,” Flores noted. “Those that can be metabolized pose decreased health risks because they can be excreted. Our major concern is accumulation of TCC in the environment and impacts on ecology by its potential endocrine disrupting effects.”

The American Chemical Society is a nonprofit organization chartered by the U.S. Congress. With more than 163,000 members, ACS is the world’s largest scientific society and a global leader in providing access to chemistry-related research through its multiple databases, peer-reviewed journals and scientific conferences. Its main offices are in Washington, D.C., and Columbus, Ohio.

Michael Bernstein | Newswise Science News
Further information:

More articles from Life Sciences:

nachricht Novel mechanisms of action discovered for the skin cancer medication Imiquimod
21.10.2016 | Technische Universität München

nachricht Second research flight into zero gravity
21.10.2016 | Universität Zürich

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: New 3-D wiring technique brings scalable quantum computers closer to reality

Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.

"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...

Im Focus: Scientists develop a semiconductor nanocomposite material that moves in response to light

In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.

A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...

Im Focus: Diamonds aren't forever: Sandia, Harvard team create first quantum computer bridge

By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.

"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...

Im Focus: New Products - Highlights of COMPAMED 2016

COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.

In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...

Im Focus: Ultra-thin ferroelectric material for next-generation electronics

'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.

Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...

All Focus news of the innovation-report >>>



Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

Agricultural Trade Developments and Potentials in Central Asia and the South Caucasus

14.10.2016 | Event News

World Health Summit – Day Three: A Call to Action

12.10.2016 | Event News

Latest News

Resolving the mystery of preeclampsia

21.10.2016 | Health and Medicine

Stanford researchers create new special-purpose computer that may someday save us billions

21.10.2016 | Information Technology

From ancient fossils to future cars

21.10.2016 | Materials Sciences

More VideoLinks >>>