Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Sea cucumbers fast track organ regrowth by healing their wounds

18.10.2007
Sea cucumbers are the champions of organ regrowth because they direct their wound healing abilities towards restoring their organs, according to research published in the online open access journal, BMC Developmental Biology.

The discovery that Holothuria glaberrima uses similar cellular mechanisms during wound healing and organ regeneration gives us the opportunity to discover how to repair our own wounds and, perhaps eventually, how to regenerate body parts.

The research was carried out by the investigators José San Miguel-Ruiz and José García-Arrarás, at the University of Puerto Rico. "Sea cucumbers should be viewed as the tissue regeneration equivalent of the squid for our knowledge of nerves and Drosophila for genes and the genome. They can help us learn to fix ourselves," commented Professor Garcia-Arraras.

"Many people, including scientists, regard sea cucumbers and other echinoderms like star fish and brittle stars as bizarre, exceptional outcasts because of their regenerative abilities. But we've shown that they use the same 'ordinary' mechanisms and processes to both regenerate and heal wounds."

... more about:
»Organ »Regeneration »healing »mechanism »repair »wound

All animals possess some kind of tissue repair mechanism. The sea cucumber, H. glaberrima, belongs to a group of marine animals that are well known for their ability to regenerate, along with the axolotl salamander, which is also famous for regrowing lost limbs. The scientists made observations over a four-week healing period and found that sea cucumbers healed up rapidly after receiving a 3 to 5 millimetre cut along the body wall.

The repair process involved special cells called morula cells moving to the injury site and full repair was achieved after just a couple of weeks. The cellular events observed during the healing of sea cucumber muscular, nervous and dermal tissues that correspond to those observed during intestinal regeneration include extracellular matrix remodeling and the dedifferentiation of muscle cells.

Although all animals have wound repair processes, not all regenerate injured or lost body parts. There must be some unusual properties of the healing processes found in animals capable of organ regeneration. So it remains to be seen at a molecular level what limits healing processes being used for regeneration by all animals in all tissue.

"Many of these regenerative mechanisms are the same as those being used by other animals to heal and repair - this includes us humans, "concluded Professor Garcia-Arraras. "Sea cucumbers will probably provide us with the key to deciphering how to regenerate our tissues, or at least find out what is needed to do this."

Charlotte Webber | alfa
Further information:
http://www.biomedcentral.com/bmcdevbiol/

Further reports about: Organ Regeneration healing mechanism repair wound

More articles from Life Sciences:

nachricht Water forms 'spine of hydration' around DNA, group finds
26.05.2017 | Cornell University

nachricht How herpesviruses win the footrace against the immune system
26.05.2017 | Helmholtz-Zentrum für Infektionsforschung

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can the immune system be boosted against Staphylococcus aureus by delivery of messenger RNA?

Staphylococcus aureus is a feared pathogen (MRSA, multi-resistant S. aureus) due to frequent resistances against many antibiotics, especially in hospital infections. Researchers at the Paul-Ehrlich-Institut have identified immunological processes that prevent a successful immune response directed against the pathogenic agent. The delivery of bacterial proteins with RNA adjuvant or messenger RNA (mRNA) into immune cells allows the re-direction of the immune response towards an active defense against S. aureus. This could be of significant importance for the development of an effective vaccine. PLOS Pathogens has published these research results online on 25 May 2017.

Staphylococcus aureus (S. aureus) is a bacterium that colonizes by far more than half of the skin and the mucosa of adults, usually without causing infections....

Im Focus: A quantum walk of photons

Physicists from the University of Würzburg are capable of generating identical looking single light particles at the push of a button. Two new studies now demonstrate the potential this method holds.

The quantum computer has fuelled the imagination of scientists for decades: It is based on fundamentally different phenomena than a conventional computer....

Im Focus: Turmoil in sluggish electrons’ existence

An international team of physicists has monitored the scattering behaviour of electrons in a non-conducting material in real-time. Their insights could be beneficial for radiotherapy.

We can refer to electrons in non-conducting materials as ‘sluggish’. Typically, they remain fixed in a location, deep inside an atomic composite. It is hence...

Im Focus: Wafer-thin Magnetic Materials Developed for Future Quantum Technologies

Two-dimensional magnetic structures are regarded as a promising material for new types of data storage, since the magnetic properties of individual molecular building blocks can be investigated and modified. For the first time, researchers have now produced a wafer-thin ferrimagnet, in which molecules with different magnetic centers arrange themselves on a gold surface to form a checkerboard pattern. Scientists at the Swiss Nanoscience Institute at the University of Basel and the Paul Scherrer Institute published their findings in the journal Nature Communications.

Ferrimagnets are composed of two centers which are magnetized at different strengths and point in opposing directions. Two-dimensional, quasi-flat ferrimagnets...

Im Focus: World's thinnest hologram paves path to new 3-D world

Nano-hologram paves way for integration of 3-D holography into everyday electronics

An Australian-Chinese research team has created the world's thinnest hologram, paving the way towards the integration of 3D holography into everyday...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Marine Conservation: IASS Contributes to UN Ocean Conference in New York on 5-9 June

24.05.2017 | Event News

AWK Aachen Machine Tool Colloquium 2017: Internet of Production for Agile Enterprises

23.05.2017 | Event News

Dortmund MST Conference presents Individualized Healthcare Solutions with micro and nanotechnology

22.05.2017 | Event News

 
Latest News

How herpesviruses win the footrace against the immune system

26.05.2017 | Life Sciences

Water forms 'spine of hydration' around DNA, group finds

26.05.2017 | Life Sciences

First Juno science results supported by University of Leicester's Jupiter 'forecast'

26.05.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>