Pharmacy student Desmond Morrow working alongside Dr Paul McCarron and Dr Ryan Donnelly from the Queen’s Medical Biology Centre have demonstrated that a novel needle free jet injection device may be a potential way of eradicating ‘difficult to treat’ skin tumours.
The breakthrough at Queen’s could benefit the growing numbers of skin cancer patients being treated with a technique called photodynamic therapy (PDT). This is where a light sensitive drug in the form of a cream is rubbed on the area affected by the cancer and a laser activates a component in the cream to destroy cancerous cells.
Desmond Morrow pointed out the importance of his findings saying: “Photodynamic therapy is a relatively new form of skin cancer treatment which results in tumour death, however, sometimes its success in individual patients is limited by the poor penetration of the active agent into the tumour. Our research shows that a new way of administering the drug can improve the amount that crosses the skin barrier and gets to the required site.”
Looking at the immediate benefit with this new form of treatment both Dr Mc Carron and Dr Donnelly commented: “In Northern Ireland, basal cell carcinoma (BBC) is a prevalent form of skin cancer. Conventional treatments for BCC include surgical excision and radiotherapy, which demonstrate acceptable clearance rates. However, both techniques are unsuitable for large or multiple lesions and can lead to poor cosmetic outcomes, such as scarring, especially on visible regions, like the face and upper torso.”
They continued: “Photodynamic therapy has been shown to eradicate certain superficial skin lesions with remarkable selectivity, giving a more satisfactory clinical outcome.”
Lisa Mitchell | alfa
The birth of a new protein
20.10.2017 | University of Arizona
Building New Moss Factories
20.10.2017 | Albert-Ludwigs-Universität Freiburg im Breisgau
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...
17.10.2017 | Event News
10.10.2017 | Event News
10.10.2017 | Event News
20.10.2017 | Information Technology
20.10.2017 | Materials Sciences
20.10.2017 | Interdisciplinary Research