Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Screen test for fragile skin

02.08.2007
White Dorper breeders and owners are hoping to eradicate a genetic disorder causing a lethal fragile skin condition among some of their drought-hardy flocks.

The disease dermatosparaxis also exists in other breeds but White Dorper breeders are the first to opt for a mass flock screening program in Australia.

"Their early adoption of a newly developed test should ensure this disease is effectively managed," NSW DPI research scientist, Dr Tracey Berg, said.

Dermatosparaxis is an inherited connective tissue disorder attributable to abnormal collagen in the skin which causes extreme skin fragility. Normal collagen provides elasticity and strength.

... more about:
»Dorper »EMAI »breed »breeder

Dermatosparaxis most often affects lambs. They suffer tearing of the skin, usually in their inner thighs and under armpits. The severity of the condition results in death or euthanasia.

Attempts to stitch the skin usually fall apart, exacerbated when animals are handled to check the repair. Mild forms of the disease have been seen in adult sheep.

"If unchecked now, there could be a potential problem for the sheep industry in the future," Angus McTaggart, federal board president of the Dorper Sheep Breeders Society of Australia, said.

The disease has been reported elsewhere in Merino, South African White Dorper and Border Leicester-Southdown sheep.

Similar conditions occur in cattle, cats and humans (Ehlers- Danlos Syndrome type VIIC).

After Brendon O’Rourke and Dr Berg confirmed and defined the disorder in Australian White Dorper flocks at the Elizabeth Macarthur Agricultural Institute (EMAI) at Camden in 2006, they then developed a DNA test to screen individual sheep for the defective gene.

They developed the test in mid-2006 at the request of breeder Malcolm Green with subsequent support from the Breeders’ Society.

"The mutation exists in sheep from most of the Australian flocks we’ve tested," Dr Berg said.

Technical assistant Nelson Jimenez selects White Dorper hairs for analysis in the Regional Veterinary Laboratory at Camden. "Of the substantial number of sheep tested, 20 per cent were carriers.

"We have also received overseas submissions and detected carriers from several countries, so it is a world wide problem."

Dr Berg and her colleagues at EMAI are consequently recommending screening of all breeding stock, or at the very minimum, screening of all sires.

"The latter is the first step in managing both damage to reputations and economic loss," former head of the Regional Veterinary Laboratory at EMAI, Dr Keith Walker, said.

"The DNA test provides an avenue for genetically smarter breeding programs."

The breed society is taking advantage of reduced rate testing by being responsible for administering samples, invoicing and reporting results.

It will also note all results on its stud book registration records, to enable public scrutiny of both positive and negative pedigree discrimination by all breeders.

A number of cattle breed societies have embraced this approach, to reduce the incidence of genetic disorders. The new genetic test is available commercially from the Genetics laboratory at EMAI.

Contact Dr Rod Reece, Camden, (02) 4640 6309, for veterinary advice about the disease, or Ian Marsh, (02) 4640 6502, about testing.

Joanne Finlay | EurekAlert!
Further information:
http://www.nsw.gov.au

Further reports about: Dorper EMAI breed breeder

More articles from Life Sciences:

nachricht New risk factors for anxiety disorders
24.02.2017 | Julius-Maximilians-Universität Würzburg

nachricht Stingless bees have their nests protected by soldiers
24.02.2017 | Johannes Gutenberg-Universität Mainz

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Breakthrough with a chain of gold atoms

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport

Im Focus: DNA repair: a new letter in the cell alphabet

Results reveal how discoveries may be hidden in scientific “blind spots”

Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...

Im Focus: Dresdner scientists print tomorrow’s world

The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.

The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...

Im Focus: Mimicking nature's cellular architectures via 3-D printing

Research offers new level of control over the structure of 3-D printed materials

Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...

Im Focus: Three Magnetic States for Each Hole

Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".

Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Booth and panel discussion – The Lindau Nobel Laureate Meetings at the AAAS 2017 Annual Meeting

13.02.2017 | Event News

Complex Loading versus Hidden Reserves

10.02.2017 | Event News

International Conference on Crystal Growth in Freiburg

09.02.2017 | Event News

 
Latest News

Stingless bees have their nests protected by soldiers

24.02.2017 | Life Sciences

New risk factors for anxiety disorders

24.02.2017 | Life Sciences

MWC 2017: 5G Capital Berlin

24.02.2017 | Trade Fair News

VideoLinks
B2B-VideoLinks
More VideoLinks >>>