Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Resistant gut bacteria will not go away by themselves

19.06.2007
E. coli bacteria that have developed resistance to antibiotics will probably still be around even if we stop using antibiotics, as these strains have the same good chance as other bacteria of continuing to colonise the gut, according to a thesis at the Sahlgrenska Academy Göteborg University in Sweden.

E. coli bacteria are found naturally in large quantities in our intestines. These bacteria do not normally cause disease, but there are several strains that can result in diarrhoea. In serious cases, they can also cause peritonitis and septicaemia.

The faeces of 128 Swedish infants were analysed in the studies underlying the thesis. The results show that 21% of E. coli strains in these infants' gut flora were resistant to at least one type of antibiotic. Even children who had never been given antibiotics had resistant bacterial strains in their intestines.

"This is a growing problem, and it's serious even when ordinary harmless bacteria develop resistance, as these genes can be transferred to more harmful bacteria," says microbiologist Nahid Karami.

... more about:
»Coli »E. coli »Karami »antibiotic »infant

Many had thought that resistant bacteria would disappear if the use of antibiotics were to be reduced, but the thesis shows that E. coli strains carrying resistance genes are just as good at colonising the gut for long periods as sensitive strains.

"Our research suggests that there's little cost to the bacteria from carrying a resistance gene, and this presumably means that this resistance will be retained for a long time by the bacteria in our gut flora even if we stop using antibiotics," says Karami.

Bacteria have a natural ability to absorb and transfer resistance genes to other bacteria. The study discovered two cases of such transfers between E. coli strains found simultaneously in a child's intestines. The first was in an infant who was treated with penicillin, and the second in an infant who was not treated with antibiotics.

"Our results suggest that the transfer of resistance genes in the gut flora may be very common, which makes the resistance issue much more serious, as genes can easily be transferred from bacteria in the normal flora to more harmful bacteria," says Karami.

Thesis presented for the title Doctor of Medicine at the Sahlgrenska Academy, Institute of Biomedicine, Department of Infectious Medicine

Title of thesis: Antibiotic resistance and fitness of Escherichia coli in the infantile commensal microbiota

The thesis is defended.

Further information: Nahid Karami, microbiologist, tel: +46 31 342 4729, mobile: +46 70 521 4860, e-mail: nahid.karami@microbio.gu.se Supervisor: Associate Professor Agnes Wold, tel: +46 31 342 4617, e-mail: agnes.wold@microbio.gu.se

Elin Lindström Claessen; +46-70 829 43 03; elin.lindstrom@sahlgrenska.gu.se

Elin Lindström | idw
Further information:
http://hdl.handle.net/2077/4418
http://www.vr.se

Further reports about: Coli E. coli Karami antibiotic infant

More articles from Life Sciences:

nachricht Nesting aids make agricultural fields attractive for bees
20.07.2017 | Julius-Maximilians-Universität Würzburg

nachricht The Kitchen Sponge – Breeding Ground for Germs
20.07.2017 | Hochschule Furtwangen

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Manipulating Electron Spins Without Loss of Information

Physicists have developed a new technique that uses electrical voltages to control the electron spin on a chip. The newly-developed method provides protection from spin decay, meaning that the contained information can be maintained and transmitted over comparatively large distances, as has been demonstrated by a team from the University of Basel’s Department of Physics and the Swiss Nanoscience Institute. The results have been published in Physical Review X.

For several years, researchers have been trying to use the spin of an electron to store and transmit information. The spin of each electron is always coupled...

Im Focus: The proton precisely weighted

What is the mass of a proton? Scientists from Germany and Japan successfully did an important step towards the most exact knowledge of this fundamental constant. By means of precision measurements on a single proton, they could improve the precision by a factor of three and also correct the existing value.

To determine the mass of a single proton still more accurate – a group of physicists led by Klaus Blaum and Sven Sturm of the Max Planck Institute for Nuclear...

Im Focus: On the way to a biological alternative

A bacterial enzyme enables reactions that open up alternatives to key industrial chemical processes

The research team of Prof. Dr. Oliver Einsle at the University of Freiburg's Institute of Biochemistry has long been exploring the functioning of nitrogenase....

Im Focus: The 1 trillion tonne iceberg

Larsen C Ice Shelf rift finally breaks through

A one trillion tonne iceberg - one of the biggest ever recorded -- has calved away from the Larsen C Ice Shelf in Antarctica, after a rift in the ice,...

Im Focus: Laser-cooled ions contribute to better understanding of friction

Physics supports biology: Researchers from PTB have developed a model system to investigate friction phenomena with atomic precision

Friction: what you want from car brakes, otherwise rather a nuisance. In any case, it is useful to know as precisely as possible how friction phenomena arise –...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

»We are bringing Additive Manufacturing to SMEs«

19.07.2017 | Event News

The technology with a feel for feelings

12.07.2017 | Event News

Leipzig HTP-Forum discusses "hydrothermal processes" as a key technology for a biobased economy

12.07.2017 | Event News

 
Latest News

Researchers create new technique for manipulating polarization of terahertz radiation

20.07.2017 | Information Technology

High-tech sensing illuminates concrete stress testing

20.07.2017 | Materials Sciences

First direct observation and measurement of ultra-fast moving vortices in superconductors

20.07.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>