Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

EMPRO Announces Phase One Clinical Trials

03.04.2007
EMPRO (European Microbicides Project), the five-year project launched in 2004 under the aegis of the EU Sixth Framework Programme (FP6) aimed at developing new microbicides to prevent HIV infection, announces phase one clinical trials.

The clinical trials to test the safety of the formulation will be conducted in the UK on a group of 46 women (one-third treated with a high-dose of antibodies, one-third with a with a low-dose of antibodies and one-third with a placebo).

The three monoclonal antibodies (C2F5, C2G12 and C4E10) developed by Polymun, an Austrian-based partner of the EMPRO Consortium, have shown therapeutic effects. For the clinical trials, the antibodies will be formulated in a gel as topically applied microbicides.

“The antibodies developed by Polymun are widely used by the scientific community for research and described in many publications. In addition their unique neutralization properties, consistent quality, high purity and absence of protein additives make them valuable tools in obtaining more reliable research results,” commented Charles Kelly, EMPRO Project Coordinator and Professor at King’s College London. “That’s why we have high hopes for the results of the phase one clinical trial and that it will prove the first step in the speedy development of an effective formulation.”

... more about:
»Clinical »EMPRO »trial

The antibodies have been designed to guide the immune system’s defences towards their target by:

- directly eliminating invading agents (e.g. in mucosal surfaces)

- neutralizing infectious agents by blocking essential steps in the infective process

- activation of sterilizing immune functions (e.g. via the complement system or cytotoxic cells).

Silvia Novembre | alfa
Further information:
http://www.empro.org.uk

Further reports about: Clinical EMPRO trial

More articles from Life Sciences:

nachricht The birth of a new protein
20.10.2017 | University of Arizona

nachricht Building New Moss Factories
20.10.2017 | Albert-Ludwigs-Universität Freiburg im Breisgau

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Terahertz spectroscopy goes nano

20.10.2017 | Information Technology

Strange but true: Turning a material upside down can sometimes make it softer

20.10.2017 | Materials Sciences

NRL clarifies valley polarization for electronic and optoelectronic technologies

20.10.2017 | Interdisciplinary Research

VideoLinks
B2B-VideoLinks
More VideoLinks >>>