Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Thioethers synthesis process

03.04.2007
Although today there exists a number of methods for the synthesis of organic molecules (the main components of certain medicines, foods, additives, paints, fabrics, liquid crystals, etc.), in most cases toxic reagents and solvents have to be used.

In these processes, moreover, contaminant waste is produced This is why coming up with a procedure that avoids these drawbacks is a good thing all round. As regards solvents, water is undoubtedly the most suitable, in this respect, due to its abundance, utility, economy, non-toxicity and environmental advantages. And what about if the key to the reaction is using the minimum quantity of catalyst? And if all that involved in the reaction (including the catalyst) is recyclable or can be directly reused?

These precisely, have been the goals of a research group of the Department of Organic Chemistry II at the University of the Basque Country (UPV-EHU) on proposing a new method for the synthesis of diaryl sulphide, objectives which, to a great extent have been met. This is because, for the invention of a method for the synthesis of thioether derivatives, diaryl sulphides are prepared in a very simple way employing a catalyst of copper salt in water. This reaction medium is recyclable. Thus, it is worth studying in depth the research work undertaken by the UPV-EHU and which is patent- protected.

Diaryl sulphides are essential components in certain medicinal drugs and their structure or “skeleton” also appears in pharmacologically efficient molecules. In any case, their methods of synthesis are limited, given that, apart from the fact that they are not viable on applying them in great quantities, they are also quite contaminant. In fact, bonding arene and sulphur (the C(aryl)-S bond) has been no easy task, historically. With the process carried out by doctors M. Carril, R. San Martín and E. Domínguez, water is the only solvent employed in the reaction; it is a cheap solvent, easily handled and does not produce any contamination. Likewise, the initial reagents (arylthiols and halides) are accessible in great quantities. The catalyst sources, i.e. the copper salts are cheap and, as the reaction is produced in an aqueous medium, there is no need for any extreme condition such as an inert atmosphere. Once the reaction is concluded, the results are extracted from the aqueous medium where the catalyst is found and the reagents and base can be added to start the reaction again. As both the solvent and the copper source can be reused, the costs savings are evident. Also, the water, unlike many solvents used in industrial processes, is not toxic, nor is it flammable. Its safety behaviour is such that no safety measure is necessary for its storage or in its handling.

... more about:
»catalyst »solvent »sulphide »synthesis

In this respect, it would be desirable for this method for the sustainable development employed in the case of diaryl sulphide to be a reality for other chemical processes.

Irati Kortabitarte | alfa
Further information:
http://www.basqueresearch.com/berria_irakurri.asp?Gelaxka=1_1&hizk=I&Berri_Kod=1264

Further reports about: catalyst solvent sulphide synthesis

More articles from Life Sciences:

nachricht Separating methane and CO2 will become more efficient
18.10.2017 | KU Leuven

nachricht Bolstering fat cells offers potential new leukemia treatment
17.10.2017 | McMaster University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Neutron star merger directly observed for the first time

University of Maryland researchers contribute to historic detection of gravitational waves and light created by event

On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...

Im Focus: Breaking: the first light from two neutron stars merging

Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.

Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....

Im Focus: Smart sensors for efficient processes

Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).

When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...

Im Focus: Cold molecules on collision course

Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.

How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...

Im Focus: Shrinking the proton again!

Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.

It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ASEAN Member States discuss the future role of renewable energy

17.10.2017 | Event News

World Health Summit 2017: International experts set the course for the future of Global Health

10.10.2017 | Event News

Climate Engineering Conference 2017 Opens in Berlin

10.10.2017 | Event News

 
Latest News

Researchers release the brakes on the immune system

18.10.2017 | Health and Medicine

Separating methane and CO2 will become more efficient

18.10.2017 | Life Sciences

Ocean atmosphere rife with microbes

17.10.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>