In these processes, moreover, contaminant waste is produced This is why coming up with a procedure that avoids these drawbacks is a good thing all round. As regards solvents, water is undoubtedly the most suitable, in this respect, due to its abundance, utility, economy, non-toxicity and environmental advantages. And what about if the key to the reaction is using the minimum quantity of catalyst? And if all that involved in the reaction (including the catalyst) is recyclable or can be directly reused?
These precisely, have been the goals of a research group of the Department of Organic Chemistry II at the University of the Basque Country (UPV-EHU) on proposing a new method for the synthesis of diaryl sulphide, objectives which, to a great extent have been met. This is because, for the invention of a method for the synthesis of thioether derivatives, diaryl sulphides are prepared in a very simple way employing a catalyst of copper salt in water. This reaction medium is recyclable. Thus, it is worth studying in depth the research work undertaken by the UPV-EHU and which is patent- protected.
Diaryl sulphides are essential components in certain medicinal drugs and their structure or “skeleton” also appears in pharmacologically efficient molecules. In any case, their methods of synthesis are limited, given that, apart from the fact that they are not viable on applying them in great quantities, they are also quite contaminant. In fact, bonding arene and sulphur (the C(aryl)-S bond) has been no easy task, historically. With the process carried out by doctors M. Carril, R. San Martín and E. Domínguez, water is the only solvent employed in the reaction; it is a cheap solvent, easily handled and does not produce any contamination. Likewise, the initial reagents (arylthiols and halides) are accessible in great quantities. The catalyst sources, i.e. the copper salts are cheap and, as the reaction is produced in an aqueous medium, there is no need for any extreme condition such as an inert atmosphere. Once the reaction is concluded, the results are extracted from the aqueous medium where the catalyst is found and the reagents and base can be added to start the reaction again. As both the solvent and the copper source can be reused, the costs savings are evident. Also, the water, unlike many solvents used in industrial processes, is not toxic, nor is it flammable. Its safety behaviour is such that no safety measure is necessary for its storage or in its handling.
In this respect, it would be desirable for this method for the sustainable development employed in the case of diaryl sulphide to be a reality for other chemical processes.
Irati Kortabitarte | alfa
Make way for the mini flying machines
21.03.2018 | American Chemical Society
New 4-D printer could reshape the world we live in
21.03.2018 | American Chemical Society
In just a few weeks from now, the Chinese space station Tiangong-1 will re-enter the Earth's atmosphere where it will to a large extent burn up. It is possible that some debris will reach the Earth's surface. Tiangong-1 is orbiting the Earth uncontrolled at a speed of approx. 29,000 km/h.Currently the prognosis relating to the time of impact currently lies within a window of several days. The scientists at Fraunhofer FHR have already been monitoring Tiangong-1 for a number of weeks with their TIRA system, one of the most powerful space observation radars in the world, with a view to supporting the German Space Situational Awareness Center and the ESA with their re-entry forecasts.
Following the loss of radio contact with Tiangong-1 in 2016 and due to the low orbital height, it is now inevitable that the Chinese space station will...
Fraunhofer Institute for Organic Electronics, Electron Beam and Plasma Technology FEP, provider of research and development services for OLED lighting solutions, announces the founding of the “OLED Licht Forum” and presents latest OLED design and lighting solutions during light+building, from March 18th – 23rd, 2018 in Frankfurt a.M./Germany, at booth no. F91 in Hall 4.0.
They are united in their passion for OLED (organic light emitting diodes) lighting with all of its unique facets and application possibilities. Thus experts in...
A new scenario seeking to explain how Mars' putative oceans came and went over the last 4 billion years implies that the oceans formed several hundred million...
For the first time, an interdisciplinary team from the University of Basel has succeeded in integrating artificial organelles into the cells of live zebrafish embryos. This innovative approach using artificial organelles as cellular implants offers new potential in treating a range of diseases, as the authors report in an article published in Nature Communications.
In the cells of higher organisms, organelles such as the nucleus or mitochondria perform a range of complex functions necessary for life. In the networks of...
Animal photoreceptors capture light with photopigments. Researchers from the University of Göttingen have now discovered that these photopigments fulfill an...
19.03.2018 | Event News
16.03.2018 | Event News
13.03.2018 | Event News
21.03.2018 | Physics and Astronomy
21.03.2018 | Materials Sciences
21.03.2018 | Life Sciences