Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Researchers study the possible relationship between myopathies and coeliac disease

23.02.2007
Inflammatory myopathies are immunological diseases that lead to inflammations in muscular tissue. As of yet, little is known about the cause of these myopathies, but it is believed to be an abnormal immune response by our bodies.

Since coeliac disease has occasionally been reported in patients with inflammatory myopathies, UAB researchers are investigating the relationship between myopathy and intolerance to gluten.

Inflammatory myopathies are inflammatory infiltrates in the muscle. This group of diseases includes polymyositis, dermatomyositis, and inclusion-body myositis. Little is known about the cause and the etiopathogenic mechanisms of these myopathies, but it is believed to be an abnormal immune response by our bodies, which identify body parts as alien. In this particular case, the body parts are the skin and the muscle, though other parts, such as the lungs and the myocardium, may also be affected.

The research team observed that it is not a rare occurrence for various autoimmune diseases to exist in the same patient. Indeed, coeliac disease -- caused by a reaction to gluten found in cereals -- has been reported in patients with inflammatory myopathy, especially those with inclusion-body myositis.

... more about:
»Gluten »coeliac »myopathies

Researchers at the Teaching Unit at the UAB's Vall d'Hebron Hospital have investigated these links by looking at coeliac patients whose cases suggest a similar immunopathogenic mechanism in coeliac disease and certain myopathies, as well as a common genetic substrate.

The scientists are considering the possibility that, at least in part, some inflammatory myopathies are a clinical expression of intolerance to gluten, though they point out the need for more studies to be carried out to confirm or support these findings. The results are particularly important in the case of inclusion-body myositis - for which there is no effective treatment - since we can now suggest that a gluten-free diet may improve the situation of a patient. This hypothesis must now be tested using immunosuppressants, as has been done with other extraintestinal manifestations of reactions to gluten.

Octavi López Coronado | alfa
Further information:
http://www.uab.es

Further reports about: Gluten coeliac myopathies

More articles from Life Sciences:

nachricht Fine organic particles in the atmosphere are more often solid glass beads than liquid oil droplets
21.04.2017 | Max-Planck-Institut für Chemie

nachricht Study overturns seminal research about the developing nervous system
21.04.2017 | University of California - Los Angeles Health Sciences

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Deep inside Galaxy M87

The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.

Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...

Im Focus: A Quantum Low Pass for Photons

Physicists in Garching observe novel quantum effect that limits the number of emitted photons.

The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...

Im Focus: Microprocessors based on a layer of just three atoms

Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.

Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...

Im Focus: Quantum-physical Model System

Computer-assisted methods aid Heidelberg physicists in reproducing experiment with ultracold atoms

Two researchers at Heidelberg University have developed a model system that enables a better understanding of the processes in a quantum-physical experiment...

Im Focus: Glacier bacteria’s contribution to carbon cycling

Glaciers might seem rather inhospitable environments. However, they are home to a diverse and vibrant microbial community. It’s becoming increasingly clear that they play a bigger role in the carbon cycle than previously thought.

A new study, now published in the journal Nature Geoscience, shows how microbial communities in melting glaciers contribute to the Earth’s carbon cycle, a...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Expert meeting “Health Business Connect” will connect international medical technology companies

20.04.2017 | Event News

Wenn der Computer das Gehirn austrickst

18.04.2017 | Event News

7th International Conference on Crystalline Silicon Photovoltaics in Freiburg on April 3-5, 2017

03.04.2017 | Event News

 
Latest News

New quantum liquid crystals may play role in future of computers

21.04.2017 | Physics and Astronomy

A promising target for kidney fibrosis

21.04.2017 | Health and Medicine

Light rays from a supernova bent by the curvature of space-time around a galaxy

21.04.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>