On February 9th, 2007, Swiss-based computational biology provider Genedata AG announced a three-year expansion of their collaboration with the HepatoSys research network. HepatoSys, an interdisciplinary initiative funded in 2003 by leading German research centers, aims to understand the physiology and pathophysiology of the human liver cell using a systems biology approach.
In the first funding period of HepatoSys, Genedata had been tasked to develop and establish a computational platform serving as the consortium's central data storage and analysis infrastructure. The platform - built on Genedata's established products Phylosopher® and Expressionist® - was successfully deployed and is now being used by the consortium. The centralized data storage infrastructure enables an integrative approach to the interpretation of systems biology modeling results in the context of experimental findings, including high-throughput transcriptomics, proteomics and metabolomics data.
Taking the collaboration to the next level, Genedata will now work on data analysis projects to interpret the huge amounts of molecular profiling data generated within the HepatoSys consortium."After having built successfully on Genedata's track record in developing our scientific computing infrastructure, we see a tremendous opportunity in bringing together our academic expertise with Genedata's know-how to transfer systems biology applications to the pharmaceutical industry," said Prof. Jens Timmer, scientific spokesman for HepatoSys.
"The ambitous goal to simulate complex biochemical networks and their regulation in liver cells is highly relevant for innovative biomedical applications," explained Prof. Irmgard Merfort, Institute for Pharmaceutical Sciences, University of Freiburg. "Cellular processes such as programmed cell death and regeneration of liver cells are of great scientific and medical interest. Genedata will help us to identify new biomarkers for disease diagnostics and to pave the way for novel therapeutic approaches in tissue regeneration, cancer and inflammation."
Dr. Othmar Pfannes, CEO of Genedata, adds: "Genedata's contributions to concrete scientific projects show that we are considered to be a valuable partner, not only on the technical, but also on the scientific side. HepatoSys is yet another long-term relationship that proves Genedata's commitment to innovative systems biology applications".
Dr. Ute Heisner | idw
http://www.systembiologie.de or http://www.genedata.com
Plant escape from waterlogging
17.10.2017 | Christian-Albrechts-Universität zu Kiel
Study suggests oysters offer hot spot for reducing nutrient pollution
17.10.2017 | Virginia Institute of Marine Science
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...
It's possible to produce hydrogen to power fuel cells by extracting the gas from seawater, but the electricity required to do it makes the process costly. UCF...
17.10.2017 | Event News
10.10.2017 | Event News
10.10.2017 | Event News
17.10.2017 | Life Sciences
17.10.2017 | Physics and Astronomy
17.10.2017 | Life Sciences