The results, reported in the latest issue of the journal Science, mark the first time scientists have been able to employ a functional nanotechnology device within a DNA array.
“It is crucial for nanorobotics to be able to insert controllable devices into a particular site within an array, thereby leading to a diversity of structural states,” explained Seeman. “Here we have demonstrated that a single device has been inserted and converted at a specific site.”
He added that the results pave the way for creating nanoscale “assembly lines” in which more complex maneuvers could be executed.
The results are based upon a device Seeman and his NYU colleagues had previously developed. That component has enabled the translation of DNA sequences, thereby potentially serving as a factory for assembling the building blocks of new materials. The invention has the potential to develop new synthetic fibers, advance the encryption of information, and improve DNA-based computation. The device, developed with NYU Chemistry graduate student Shiping Liao, emulates the process by which RNA replicas of DNA sequences are translated to create protein sequences. However, the signals that control the nanomechanical tool are DNA rather than RNA. The dimensions of the machine are approximately 110 x 30 x 2 nm.
In this study, Seeman and Ding developed a framework that contains a binding site--a cassette—that allows insertion of the device into a specific site of a DNA array. Changing the cassette’s control sequences or insertion sequences would allow the researchers to manipulate the array or insert it at different locations. The researchers added a long arm to the framework so that they could observe the structure undergoing a half-rotation. They visualized their results by atomic force microscopy (AFM), which permits features that are a few billionths of a meter to be visualized.
James Devitt | EurekAlert!
Single-stranded DNA and RNA origami go live
15.12.2017 | Wyss Institute for Biologically Inspired Engineering at Harvard
New antbird species discovered in Peru by LSU ornithologists
15.12.2017 | Louisiana State University
DNA molecules that follow specific instructions could offer more precise molecular control of synthetic chemical systems, a discovery that opens the door for engineers to create molecular machines with new and complex behaviors.
Researchers have created chemical amplifiers and a chemical oscillator using a systematic method that has the potential to embed sophisticated circuit...
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
11.12.2017 | Event News
08.12.2017 | Event News
07.12.2017 | Event News
15.12.2017 | Power and Electrical Engineering
15.12.2017 | Materials Sciences
15.12.2017 | Life Sciences