The results, reported in the latest issue of the journal Science, mark the first time scientists have been able to employ a functional nanotechnology device within a DNA array.
“It is crucial for nanorobotics to be able to insert controllable devices into a particular site within an array, thereby leading to a diversity of structural states,” explained Seeman. “Here we have demonstrated that a single device has been inserted and converted at a specific site.”
He added that the results pave the way for creating nanoscale “assembly lines” in which more complex maneuvers could be executed.
The results are based upon a device Seeman and his NYU colleagues had previously developed. That component has enabled the translation of DNA sequences, thereby potentially serving as a factory for assembling the building blocks of new materials. The invention has the potential to develop new synthetic fibers, advance the encryption of information, and improve DNA-based computation. The device, developed with NYU Chemistry graduate student Shiping Liao, emulates the process by which RNA replicas of DNA sequences are translated to create protein sequences. However, the signals that control the nanomechanical tool are DNA rather than RNA. The dimensions of the machine are approximately 110 x 30 x 2 nm.
In this study, Seeman and Ding developed a framework that contains a binding site--a cassette—that allows insertion of the device into a specific site of a DNA array. Changing the cassette’s control sequences or insertion sequences would allow the researchers to manipulate the array or insert it at different locations. The researchers added a long arm to the framework so that they could observe the structure undergoing a half-rotation. They visualized their results by atomic force microscopy (AFM), which permits features that are a few billionths of a meter to be visualized.
James Devitt | EurekAlert!
The birth of a new protein
20.10.2017 | University of Arizona
Building New Moss Factories
20.10.2017 | Albert-Ludwigs-Universität Freiburg im Breisgau
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
Scientists from the Max Planck Institute of Quantum Optics, using high precision laser spectroscopy of atomic hydrogen, confirm the surprisingly small value of the proton radius determined from muonic hydrogen.
It was one of the breakthroughs of the year 2010: Laser spectroscopy of muonic hydrogen resulted in a value for the proton charge radius that was significantly...
17.10.2017 | Event News
10.10.2017 | Event News
10.10.2017 | Event News
20.10.2017 | Information Technology
20.10.2017 | Materials Sciences
20.10.2017 | Interdisciplinary Research