Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

International Initiative to Understand the Function of All Genes Has Started

13.09.2006
The Conditional Mouse Mutagenesis Program EUCOMM, funded by the European Union with € 13 million, and its Canadian partner project NorCOMM are getting support from the US: today, 7 September, the Knockout Mouse Project (KOMP) of the American National Institutes of Health (NIH) was launched. In close cooperation the three big projects want to mutate practically all genes of the mouse genome, in order to be able to understand the function of all genes with the help of mouse models.

European scientists have been pioneers in this initiative, the structure of which is going to be similar to that of the International Human Genome Project carried out earlier. Since the beginning of the year EUCOMM has already been producing mutated mouse genes in embryonic stem cells of the mouse, which will soon be made freely available to the scientific community. From these cells mouse models can be generated for all human diseases with genetic causes.

The European program is coordinated by Prof. Dr. Wolfgang Wurst, Director of the Institute of Developmental Genetics at the GSF – National Research Center for Environment and Health, Munich/Neuherberg, Germany. Wurst, his team, and the German Gene Trap Consortium (GGTC), funded by the German Federal Ministry of Education and Research, in the past developed part of the methods applied in the new projects and, thereby, made EUCOMM possible in the first place.

The methods used for the mutation of the mouse genes are conditional gene trapping and gene targeting technologies, which allow a particularly precise modelling of genetic diseases in the mouse, i.e. of Morbus Parkinson, cancer, cardiovascular diseases, and others.

... more about:
»EUCOMM »diseases

EUCOMM raises the production of mouse models to a new level, because the models can now be generated in a coordinated manner as well as faster, more easily and at lower cost than in the past. This means that the decipherment of the mechanisms of all genetically caused diseases is becoming tangible.

Michael van den Heuvel | alfa
Further information:
http://www.gsf.de/neu/Aktuelles/Presse/2006/KOMP_en.php

Further reports about: EUCOMM diseases

More articles from Life Sciences:

nachricht Researchers identify potentially druggable mutant p53 proteins that promote cancer growth
09.12.2016 | Cold Spring Harbor Laboratory

nachricht Plant-based substance boosts eyelash growth
09.12.2016 | Fraunhofer-Institut für Angewandte Polymerforschung IAP

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Electron highway inside crystal

Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.

Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...

Im Focus: Significantly more productivity in USP lasers

In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.

Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...

Im Focus: Shape matters when light meets atom

Mapping the interaction of a single atom with a single photon may inform design of quantum devices

Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...

Im Focus: Novel silicon etching technique crafts 3-D gradient refractive index micro-optics

A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.

Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...

Im Focus: Quantum Particles Form Droplets

In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.

“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

ICTM Conference 2017: Production technology for turbomachine manufacturing of the future

16.11.2016 | Event News

Innovation Day Laser Technology – Laser Additive Manufacturing

01.11.2016 | Event News

#IC2S2: When Social Science meets Computer Science - GESIS will host the IC2S2 conference 2017

14.10.2016 | Event News

 
Latest News

Researchers identify potentially druggable mutant p53 proteins that promote cancer growth

09.12.2016 | Life Sciences

Scientists produce a new roadmap for guiding development & conservation in the Amazon

09.12.2016 | Ecology, The Environment and Conservation

Satellites, airport visibility readings shed light on troops' exposure to air pollution

09.12.2016 | Health and Medicine

VideoLinks
B2B-VideoLinks
More VideoLinks >>>