The idea grew out of collaboration between a professor of medicinal and physiological chemistry, Charlotte Erlanson-Albertsson, who does research on obesity and appetite control, and her husband Per-Åke Albertsson, a professor of biochemistry, who does research on photosynthesis in plants.
Their point of departure is that a substance that inhibits the degradation of fat should make fat stay in the intestines longer, thereby creating a longer-lasting feeling of satiety after a meal.
A certain substance in the so-called tylakoids seems to have just such a function. The tylakoids are tiny membranes in the chloroplasts, those parts of a plant cell where photosynthesis takes place. They contain proteins, minerals, and fat.
The two Lund professors started experimenting on themselves last summer. They ate tylakoids and tried to gage whether the feeling of satiety after a meal lasted longer. Then Charlotte Erlanson-Albertsson’s research team went on to run tests where rats were fed a fat-rich diet with and without tylakoid supplements.
The results showed that rats receiving the supplement actually gained less weight. These rats also had lower blood sugar levels and lower blood fats, which if the results are the same for humans is good for the health. The scientists now plan to move on to experiments on humans on a fat-rich diet and on rats eating a sugar-rich diet.
Spinach provides the leaves the Lund team is using in its experiments.
“But if you were to use raw spinach as a source of tylakoids, you would have to eat about a half a kilo of spinach a day. When we isolate and purify the substance, we only need a few grams. The idea is that it should be possible to add the substance to fat-rich products such as pies or cookies,” says doctoral candidate Rikard Köhnke.
It is not known precisely how tylakoids go about inhibiting the degradation of fat in the intestines. The researchers’ theory is that they form a coating around the drops of fat, so that the enzymes that are meant to cleave the fat cannot do so as rapidly as usual.
Ingela Björck | alfa
A novel socio-ecological approach helps identifying suitable wolf habitats
17.02.2017 | Universität Zürich
New, ultra-flexible probes form reliable, scar-free integration with the brain
16.02.2017 | University of Texas at Austin
In the field of nanoscience, an international team of physicists with participants from Konstanz has achieved a breakthrough in understanding heat transport
Cells need to repair damaged DNA in our genes to prevent the development of cancer and other diseases. Our cells therefore activate and send “repair-proteins”...
The Fraunhofer IWS Dresden and Technische Universität Dresden inaugurated their jointly operated Center for Additive Manufacturing Dresden (AMCD) with a festive ceremony on February 7, 2017. Scientists from various disciplines perform research on materials, additive manufacturing processes and innovative technologies, which build up components in a layer by layer process. This technology opens up new horizons for component design and combinations of functions. For example during fabrication, electrical conductors and sensors are already able to be additively manufactured into components. They provide information about stress conditions of a product during operation.
The 3D-printing technology, or additive manufacturing as it is often called, has long made the step out of scientific research laboratories into industrial...
Nature does amazing things with limited design materials. Grass, for example, can support its own weight, resist strong wind loads, and recover after being...
Nanometer-scale magnetic perforated grids could create new possibilities for computing. Together with international colleagues, scientists from the Helmholtz Zentrum Dresden-Rossendorf (HZDR) have shown how a cobalt grid can be reliably programmed at room temperature. In addition they discovered that for every hole ("antidot") three magnetic states can be configured. The results have been published in the journal "Scientific Reports".
Physicist Dr. Rantej Bali from the HZDR, together with scientists from Singapore and Australia, designed a special grid structure in a thin layer of cobalt in...
13.02.2017 | Event News
10.02.2017 | Event News
09.02.2017 | Event News
20.02.2017 | Materials Sciences
20.02.2017 | Health and Medicine
20.02.2017 | Health and Medicine