Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Preclinical costs reduced by new human cell culture system from Northern Germany

02.06.2006
The young biotech start up company PRIMACYT has developed a long-term human hepatocyte culture system that may be used as a biosensor for the analysis of drugs, food additives, and chemicals. The entrepreneur team has developed serum-free long-term culture techniques for hepatocytes. Currently, several other companies are validating this culture technique in a multi-center study. The technology is presented on international conferences in San Francisco, USA April 2006 and Linz, Austria June 2006.

The PRIMACYT Cell Culture Technology GmbH has developed serum-free long-term culture techniques for hepatocytes. These technologies allow utilization of human and other mammalian hepatocytes as biosensors for screening purposes, while the hepatocyte specific functions remain intact. On this basis, new innovative products and services will be created to provide pharmaceutical and biotech companies as well as public research institutions with state of the art solutions for their specific demands.


Mikroskopische Aufnahme einer humanen Leberzelle, Primacyt GmbH

The major advantages of this hepatocyte culture system are its robustness and the fact that the hepatocytes remain differentiated and functional for several weeks. Preliminary studies have revealed that repetitive cycles of drug administrations can be applied to the cells. In other words, the hepatocytes may not only be used for one experiment, but instead can be "recycled" and may be used for a second, a third or even a fourth round of experiments. Thereby, the system is designed to reduce the number of animal experiments and to reduce the costs of preclinical studies.

The company is presenting its human hepatocyte culture system HEPAC2 at the annual Experimental Biology meeting in San Francisco, April 1-5, and at the 13th Conference on Alternatives to Animal Testing in Linz, Austria, on June 2-4. "These are a great opportunities for our company to demonstrate the advantages of our culture system to a broad audience" said Dr. Dieter Runge, co-founder and CEO of this young biotech company.

PRIMACYT Cell Culture Technology GmbH has its roots in HeparCell GmbH, originally founded by 4 private individuals in June 2004. In December 2004 HeparCell completed a private financing round led by Genius Venture Capital GmbH. In January 2005 HeparCell started its business at the Technologie- und Gewerbezentrum Schwerin. In October 2005 HeparCell GmbH changed its corporate name to PRIMACYT Cell Culture Technology. PRIMACYT is member of BioCon Valley.

BioCon Valley is the initiative for Life Science and health economy of Mecklenburg-Vorpommern, Germany. As one of the German BioRegions BioCon Valley supports the commercial use of modern life sciences and bio- and medical technologies in the region. BioCon Valley s tasks are networking, managing life science centers (bioincubators), project management and coordination, and life science specific public relation. BioCon Valley collaborates in strategic partnership to the life science initiatives at the Baltic Sea (www.scanbalt.org).

Contact:
PRIMACYT Cell Culture Technology GmbH
Dr. Dieter Runge
Hagenower Straße 73
19061 Schwerin
Germany
Telefon: +49 (0)385 - 3993 600
Telefax: +49 (0)385 - 3993 602
E-mail: info@primacyt.de

Dr. Heinrich Cuypers | idw
Further information:
http://www.primacyt.de
http://www.bcv.org

More articles from Life Sciences:

nachricht Unique genome architectures after fertilisation in single-cell embryos
30.03.2017 | IMBA - Institut für Molekulare Biotechnologie der Österreichischen Akademie der Wissenschaften GmbH

nachricht Transport of molecular motors into cilia
28.03.2017 | Aarhus University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Challenging European Research Project to Develop New Tiny Microscopes

The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.

To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

'On-off switch' brings researchers a step closer to potential HIV vaccine

30.03.2017 | Health and Medicine

Penn studies find promise for innovations in liquid biopsies

30.03.2017 | Health and Medicine

An LED-based device for imaging radiation induced skin damage

30.03.2017 | Medical Engineering

VideoLinks
B2B-VideoLinks
More VideoLinks >>>