In order to perform the study she began with prior studies from her laboratory, which demonstrated that the protein aCP4 appears in the tissue cells that coat the normal lung, and which, nevertheless, are lost in the first phases of lung cancer as well as in 67% percent of the tumors observed.
The new Doctor in Biochemistry extracted various cellular lines of different types of lung tumors and introduced a sequence of the protein aCP4 in order to observe the resulting effects. In some of the cells she demonstrated that the tumor proliferation was reduced. In particular, in malignant tumors of large cells she observed that their capacity for growth was reduced, independently of their anchoring or invasive capacity, two key characteristics for production of metastasis.
Lung cancer is one of the major causes of death, along with cardiovascular diseases, both in Europe and in the U.S., due to the fact that it is generally detected at a late stage when the disease is nearly incurable. Therefore it is necessary to develop new strategies that permit the detection of tumors of smaller size, biomarkers that make early detection possible, as well as a greater understanding of the alterations that occur. All of this in order to discover specific therapies for correcting these errors.
Irati Kortabitarte | alfa
BigH1 -- The key histone for male fertility
14.12.2017 | Institute for Research in Biomedicine (IRB Barcelona)
Guardians of the Gate
14.12.2017 | Max-Planck-Institut für Biochemie
MPQ scientists achieve long storage times for photonic quantum bits which break the lower bound for direct teleportation in a global quantum network.
Concerning the development of quantum memories for the realization of global quantum networks, scientists of the Quantum Dynamics Division led by Professor...
Researchers have developed a water cloaking concept based on electromagnetic forces that could eliminate an object's wake, greatly reducing its drag while...
Tiny pores at a cell's entryway act as miniature bouncers, letting in some electrically charged atoms--ions--but blocking others. Operating as exquisitely sensitive filters, these "ion channels" play a critical role in biological functions such as muscle contraction and the firing of brain cells.
To rapidly transport the right ions through the cell membrane, the tiny channels rely on a complex interplay between the ions and surrounding molecules,...
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...
11.12.2017 | Event News
08.12.2017 | Event News
07.12.2017 | Event News
14.12.2017 | Health and Medicine
14.12.2017 | Physics and Astronomy
14.12.2017 | Life Sciences