Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New light on muscle efficiency: it is not the power-plant.

23.03.2006
A recent study from Scandinavia shows that the well-known differences between individuals in the efficiency of converting energy stored in food to work done by muscles are related to muscle fibre type composition and to the content of specific molecules in muscle.

When muscles contract they use energy that is derived from food. It is a two-step process. The first step occurs in mitochondria, where the energy from molecules like glucose or fats is locked away in ATP (adenosine triphosphate). This ATP travels from the mitochondria to sites in the muscle where energy is needed, and the energy is released and used. At both of these stages there is the possibility for energy to be lost, causing a reduction in efficiency. The proportion of food energy that ends up making the muscles move is a measure of the efficiency of the system, and this is known to vary considerably between people.

The main theory is that this variation comes from differences in the efficiency with which mitochondria convert food energy to ATP. But results published in this fortnight’s edition of The Journal of Physiology indicate that any differences in the efficiency of individual mitochondria cannot explain the differences in overall efficiency between people. Consequently these differences must lie in the way the ATP is used within the muscle.

The research was carried out on healthy human volunteers by a team of scientists working at the University of Southern Denmark, Odense, and the Karolinska Institute/GIH, in Stockholm, Sweden. It combined exercise testing of individuals, with laboratory analysis of muscle samples.

The results showed that work efficiency was correlated with muscle fibre type composition and with the amount of UCP3 protein – muscles with high proportions of this protein had lower efficiencies than those with low proportions.

“It’s too early to say whether UCP3 causes this difference, or whether it is a marker of some other process, but further research might someday lead to training strategies that will help us improve efficiency, or identify subjects who have the potential to become more efficient over time,” says lead author Martin Mogensen.

“The work is an excellent example of integrative physiology, addressing questions both at the sub-cellular and whole body levels that have implications for basic muscle energetics as well as athletic performance,” says Professor Edward Coyle, of the University of Texas at Austin, in an accompanying editorial.

Lucy Mansfield | alfa
Further information:
http://www.blackwellpublishing.com/tjp

More articles from Life Sciences:

nachricht Transport of molecular motors into cilia
28.03.2017 | Aarhus University

nachricht Asian dust providing key nutrients for California's giant sequoias
28.03.2017 | University of California - Riverside

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: A Challenging European Research Project to Develop New Tiny Microscopes

The Institute of Semiconductor Technology and the Institute of Physical and Theoretical Chemistry, both members of the Laboratory for Emerging Nanometrology (LENA), at Technische Universität Braunschweig are partners in a new European research project entitled ChipScope, which aims to develop a completely new and extremely small optical microscope capable of observing the interior of living cells in real time. A consortium of 7 partners from 5 countries will tackle this issue with very ambitious objectives during a four-year research program.

To demonstrate the usefulness of this new scientific tool, at the end of the project the developed chip-sized microscope will be used to observe in real-time...

Im Focus: Giant Magnetic Fields in the Universe

Astronomers from Bonn and Tautenburg in Thuringia (Germany) used the 100-m radio telescope at Effelsberg to observe several galaxy clusters. At the edges of these large accumulations of dark matter, stellar systems (galaxies), hot gas, and charged particles, they found magnetic fields that are exceptionally ordered over distances of many million light years. This makes them the most extended magnetic fields in the universe known so far.

The results will be published on March 22 in the journal „Astronomy & Astrophysics“.

Galaxy clusters are the largest gravitationally bound structures in the universe. With a typical extent of about 10 million light years, i.e. 100 times the...

Im Focus: Tracing down linear ubiquitination

Researchers at the Goethe University Frankfurt, together with partners from the University of Tübingen in Germany and Queen Mary University as well as Francis Crick Institute from London (UK) have developed a novel technology to decipher the secret ubiquitin code.

Ubiquitin is a small protein that can be linked to other cellular proteins, thereby controlling and modulating their functions. The attachment occurs in many...

Im Focus: Perovskite edges can be tuned for optoelectronic performance

Layered 2D material improves efficiency for solar cells and LEDs

In the eternal search for next generation high-efficiency solar cells and LEDs, scientists at Los Alamos National Laboratory and their partners are creating...

Im Focus: Polymer-coated silicon nanosheets as alternative to graphene: A perfect team for nanoelectronics

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are less stable. Now researchers at the Technical University of Munich (TUM) have, for the first time ever, produced a composite material combining silicon nanosheets and a polymer that is both UV-resistant and easy to process. This brings the scientists a significant step closer to industrial applications like flexible displays and photosensors.

Silicon nanosheets are thin, two-dimensional layers with exceptional optoelectronic properties very similar to those of graphene. Albeit, the nanosheets are...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

International Land Use Symposium ILUS 2017: Call for Abstracts and Registration open

20.03.2017 | Event News

CONNECT 2017: International congress on connective tissue

14.03.2017 | Event News

ICTM Conference: Turbine Construction between Big Data and Additive Manufacturing

07.03.2017 | Event News

 
Latest News

Researchers shoot for success with simulations of laser pulse-material interactions

29.03.2017 | Materials Sciences

Igniting a solar flare in the corona with lower-atmosphere kindling

29.03.2017 | Physics and Astronomy

As sea level rises, much of Honolulu and Waikiki vulnerable to groundwater inundation

29.03.2017 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>