Presentations: American Heart Association Scientific Sessions 2005
Cardiology researchers at Cedars-Sinai Medical Center have found that a single injection of a harmless virus engineered to carry a beneficial, mutant gene enabled animals to manufacture their own supply of the genes protein product that protects against plaque buildup in blood vessels. As a result, the amount of plaque was significantly reduced, as was an immune reaction that can lead to plaque buildup and rupture, which can cause a blocked artery and heart attack or stroke.
The researchers will present their findings from this and other studies at the American Heart Association Scientific Sessions 2005 Nov. 13 through 16 in Dallas. They are pursuing a variety of approaches to interrupt the complex processes leading to plaque formation and rupture, seeking new ways to treat and even prevent atherosclerosis.
Sandy Van | EurekAlert!
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