Tiny worms that can trick the bodys natural defences could hold the key to new treatments for a range of conditions, including diabetes, asthma and hay fever. University of Edinburgh scientists, who have discovered that helminth parasites can exploit an Achilles heel in our immune system, now hope to mimic the worms survival tactics in a bid to beat infection.
To find out how helminths fool the bodys defences, the team are focusing on the role played by so-called regulatory cells, which fulfil a policing role that protects our bodies. These cells decide when to stop the immune system from attacking the bodys own proteins (a process called autoimmunity) and also prevent it from attacking harmless environmental molecules.
It is thought that helminths produce molecules that trigger a response in regulatory cells (similar to the one that prevents autoimmunity), which tricks the body into switching off the response that would otherwise kill the parasites. If that is the case, then infections could be cured, not by vaccination or drug treatment, but by reactivating the immune system. It is the first time such a concept has been explored to curb the tropical diseases caused by helminths – such as filariasis and schistosomiasis – which affect one in four of the global population.
Ronald Kerr | EurekAlert!
Molecular libraries for organic light-emitting diodes
24.04.2017 | Goethe-Universität Frankfurt am Main
Fine organic particles in the atmosphere are more often solid glass beads than liquid oil droplets
21.04.2017 | Max-Planck-Institut für Chemie
More and more automobile companies are focusing on body parts made of carbon fiber reinforced plastics (CFRP). However, manufacturing and repair costs must be further reduced in order to make CFRP more economical in use. Together with the Volkswagen AG and five other partners in the project HolQueSt 3D, the Laser Zentrum Hannover e.V. (LZH) has developed laser processes for the automatic trimming, drilling and repair of three-dimensional components.
Automated manufacturing processes are the basis for ultimately establishing the series production of CFRP components. In the project HolQueSt 3D, the LZH has...
Reflecting the structure of composites found in nature and the ancient world, researchers at the University of Illinois at Urbana-Champaign have synthesized thin carbon nanotube (CNT) textiles that exhibit both high electrical conductivity and a level of toughness that is about fifty times higher than copper films, currently used in electronics.
"The structural robustness of thin metal films has significant importance for the reliable operation of smart skin and flexible electronics including...
The nearby, giant radio galaxy M87 hosts a supermassive black hole (BH) and is well-known for its bright jet dominating the spectrum over ten orders of magnitude in frequency. Due to its proximity, jet prominence, and the large black hole mass, M87 is the best laboratory for investigating the formation, acceleration, and collimation of relativistic jets. A research team led by Silke Britzen from the Max Planck Institute for Radio Astronomy in Bonn, Germany, has found strong indication for turbulent processes connecting the accretion disk and the jet of that galaxy providing insights into the longstanding problem of the origin of astrophysical jets.
Supermassive black holes form some of the most enigmatic phenomena in astrophysics. Their enormous energy output is supposed to be generated by the...
The probability to find a certain number of photons inside a laser pulse usually corresponds to a classical distribution of independent events, the so-called...
Microprocessors based on atomically thin materials hold the promise of the evolution of traditional processors as well as new applications in the field of flexible electronics. Now, a TU Wien research team led by Thomas Müller has made a breakthrough in this field as part of an ongoing research project.
Two-dimensional materials, or 2D materials for short, are extremely versatile, although – or often more precisely because – they are made up of just one or a...
20.04.2017 | Event News
18.04.2017 | Event News
03.04.2017 | Event News
24.04.2017 | Life Sciences
24.04.2017 | Earth Sciences
24.04.2017 | Machine Engineering