Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Comparison of cocaine and methamphetamine ’highs’ finds differences in onset, pattern and duration

25.08.2005


Investigators at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA examining responses to cocaine and methamphetamine use find distinct differences in onset, pattern and duration.



Subjective, or self-reported, responses to cocaine peak and decline more rapidly than those of methamphetamine, the study shows. Cardiovascular responses to the two stimulants are similar at onset but responses to cocaine decline more rapidly.

In press with the peer-reviewed journal Pharmacology, Biochemistry and Behavior, the study is the first to use identical procedures in measuring and comparing subjective and cardiovascular responses to the two stimulants.


"These differences help explain patterns of use by addicts. Methamphetamine users, for instance, report using the drug daily throughout each day, while cocaine users typically engage in binges that occur most often in the evening," said Dr. Thomas F. Newton, the study’s principal investigator and a research scientist at the Semel Institute.

"In addition, the study results may impact development of medication treatments for addiction to these two very different stimulants," said Newton, a professor of psychiatry and biobehavioral sciences at the David Geffen School of Medicine at UCLA.

The study examined the onset, pattern and duration of the response to cocaine in 14 cocaine dependent volunteers and the response to methamphetamine in 11 methamphetamine dependent volunteers. None of the volunteers were seeking treatment.

Study volunteers reported subjective effects using a sliding rating scale ranging from 0, or "no drug effect," to 100, "most drug effect ever." Ratings were obtained just prior to administration of the drug and at regular intervals for 30 minutes following administration.

Heart rate and blood pressures were assessed using an automated device just prior to administration of the drug and at regular intervals for 60 minutes following administration.

Dan Page | EurekAlert!
Further information:
http://www.mednet.ucla.edu
http://www.npi.ucla.edu/
http://www.medsch.ucla.edu/

More articles from Life Sciences:

nachricht Toward a 'smart' patch that automatically delivers insulin when needed
18.01.2017 | American Chemical Society

nachricht 127 at one blow...
18.01.2017 | Stiftung Zoologisches Forschungsmuseum Alexander Koenig, Leibniz-Institut für Biodiversität der Tiere

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

Im Focus: How to inflate a hardened concrete shell with a weight of 80 t

At TU Wien, an alternative for resource intensive formwork for the construction of concrete domes was developed. It is now used in a test dome for the Austrian Federal Railways Infrastructure (ÖBB Infrastruktur).

Concrete shells are efficient structures, but not very resource efficient. The formwork for the construction of concrete domes alone requires a high amount of...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

Nothing will happen without batteries making it happen!

05.01.2017 | Event News

 
Latest News

A big nano boost for solar cells

18.01.2017 | Power and Electrical Engineering

Glass's off-kilter harmonies

18.01.2017 | Materials Sciences

Toward a 'smart' patch that automatically delivers insulin when needed

18.01.2017 | Life Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>