Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Comparison of cocaine and methamphetamine ’highs’ finds differences in onset, pattern and duration

25.08.2005


Investigators at the Jane and Terry Semel Institute for Neuroscience and Human Behavior at UCLA examining responses to cocaine and methamphetamine use find distinct differences in onset, pattern and duration.



Subjective, or self-reported, responses to cocaine peak and decline more rapidly than those of methamphetamine, the study shows. Cardiovascular responses to the two stimulants are similar at onset but responses to cocaine decline more rapidly.

In press with the peer-reviewed journal Pharmacology, Biochemistry and Behavior, the study is the first to use identical procedures in measuring and comparing subjective and cardiovascular responses to the two stimulants.


"These differences help explain patterns of use by addicts. Methamphetamine users, for instance, report using the drug daily throughout each day, while cocaine users typically engage in binges that occur most often in the evening," said Dr. Thomas F. Newton, the study’s principal investigator and a research scientist at the Semel Institute.

"In addition, the study results may impact development of medication treatments for addiction to these two very different stimulants," said Newton, a professor of psychiatry and biobehavioral sciences at the David Geffen School of Medicine at UCLA.

The study examined the onset, pattern and duration of the response to cocaine in 14 cocaine dependent volunteers and the response to methamphetamine in 11 methamphetamine dependent volunteers. None of the volunteers were seeking treatment.

Study volunteers reported subjective effects using a sliding rating scale ranging from 0, or "no drug effect," to 100, "most drug effect ever." Ratings were obtained just prior to administration of the drug and at regular intervals for 30 minutes following administration.

Heart rate and blood pressures were assessed using an automated device just prior to administration of the drug and at regular intervals for 60 minutes following administration.

Dan Page | EurekAlert!
Further information:
http://www.mednet.ucla.edu
http://www.npi.ucla.edu/
http://www.medsch.ucla.edu/

More articles from Life Sciences:

nachricht Polymers Based on Boron?
18.01.2018 | Julius-Maximilians-Universität Würzburg

nachricht Bioengineered soft microfibers improve T-cell production
18.01.2018 | Columbia University School of Engineering and Applied Science

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Scientists decipher key principle behind reaction of metalloenzymes

So-called pre-distorted states accelerate photochemical reactions too

What enables electrons to be transferred swiftly, for example during photosynthesis? An interdisciplinary team of researchers has worked out the details of how...

Im Focus: The first precise measurement of a single molecule's effective charge

For the first time, scientists have precisely measured the effective electrical charge of a single molecule in solution. This fundamental insight of an SNSF Professor could also pave the way for future medical diagnostics.

Electrical charge is one of the key properties that allows molecules to interact. Life itself depends on this phenomenon: many biological processes involve...

Im Focus: Paradigm shift in Paris: Encouraging an holistic view of laser machining

At the JEC World Composite Show in Paris in March 2018, the Fraunhofer Institute for Laser Technology ILT will be focusing on the latest trends and innovations in laser machining of composites. Among other things, researchers at the booth shared with the Aachen Center for Integrative Lightweight Production (AZL) will demonstrate how lasers can be used for joining, structuring, cutting and drilling composite materials.

No other industry has attracted as much public attention to composite materials as the automotive industry, which along with the aerospace industry is a driver...

Im Focus: Room-temperature multiferroic thin films and their properties

Scientists at Tokyo Institute of Technology (Tokyo Tech) and Tohoku University have developed high-quality GFO epitaxial films and systematically investigated their ferroelectric and ferromagnetic properties. They also demonstrated the room-temperature magnetocapacitance effects of these GFO thin films.

Multiferroic materials show magnetically driven ferroelectricity. They are attracting increasing attention because of their fascinating properties such as...

Im Focus: A thermometer for the oceans

Measurement of noble gases in Antarctic ice cores

The oceans are the largest global heat reservoir. As a result of man-made global warming, the temperature in the global climate system increases; around 90% of...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

10th International Symposium: “Advanced Battery Power – Kraftwerk Batterie” Münster, 10-11 April 2018

08.01.2018 | Event News

See, understand and experience the work of the future

11.12.2017 | Event News

Innovative strategies to tackle parasitic worms

08.12.2017 | Event News

 
Latest News

Polymers Based on Boron?

18.01.2018 | Life Sciences

Bioengineered soft microfibers improve T-cell production

18.01.2018 | Life Sciences

World’s oldest known oxygen oasis discovered

18.01.2018 | Earth Sciences

VideoLinks
B2B-VideoLinks
More VideoLinks >>>