The blood-thinning drug Warfarin tops the list of drug side-effects in Sweden. Patient sensitivity to Warfarin varies, which can lead to over-dosage and in certain cases to death. A study led by Mia Wadelius at Uppsala University in Sweden, together with researchers in Cambridge, indicates that two genes may be the explanation. The findings are being published in the latest issue of The Pharmacogenomics Journal.
Warfarin is used to prevent blood clots, but a side-effect can be severe, even fatal, bleeding. In Sweden since the 1960s more fatal side-effects have been reported from Warfarin than for any other drug. Of the 118 deaths reported in connection with drug treatment in Sweden last year, nearly half involved bleeding from Warfarin.
There is still no good alternative to Warfarin in cases of blood clots or heart or valve diseases. Every year 70,000 patients in Sweden are treated with Warfarin. All patients receive the same dose the first few days, then the dosage is determined by a test of the capacity of the blood to coagulate. The differences are great in how much Warfarin patients need to attain an effect. One patient can require 20 times the dose needed by another patient.
Making fuel out of thick air
08.12.2017 | DOE/Argonne National Laboratory
‘Spying’ on the hidden geometry of complex networks through machine intelligence
08.12.2017 | Technische Universität Dresden
The miniaturization of the current technology of storage media is hindered by fundamental limits of quantum mechanics. A new approach consists in using so-called spin-crossover molecules as the smallest possible storage unit. Similar to normal hard drives, these special molecules can save information via their magnetic state. A research team from Kiel University has now managed to successfully place a new class of spin-crossover molecules onto a surface and to improve the molecule’s storage capacity. The storage density of conventional hard drives could therefore theoretically be increased by more than one hundred fold. The study has been published in the scientific journal Nano Letters.
Over the past few years, the building blocks of storage media have gotten ever smaller. But further miniaturization of the current technology is hindered by...
With innovative experiments, researchers at the Helmholtz-Zentrums Geesthacht and the Technical University Hamburg unravel why tiny metallic structures are extremely strong
Light-weight and simultaneously strong – porous metallic nanomaterials promise interesting applications as, for instance, for future aeroplanes with enhanced...
An interdisciplinary group of researchers interfaced individual bacteria with a computer to build a hybrid bio-digital circuit - Study published in Nature Communications
Scientists at the Institute of Science and Technology Austria (IST Austria) have managed to control the behavior of individual bacteria by connecting them to a...
Physicists in the Laboratory for Attosecond Physics (run jointly by LMU Munich and the Max Planck Institute for Quantum Optics) have developed an attosecond electron microscope that allows them to visualize the dispersion of light in time and space, and observe the motions of electrons in atoms.
The most basic of all physical interactions in nature is that between light and matter. This interaction takes place in attosecond times (i.e. billionths of a...
Transistors based on carbon nanostructures: what sounds like a futuristic dream could be reality in just a few years' time. An international research team working with Empa has now succeeded in producing nanotransistors from graphene ribbons that are only a few atoms wide, as reported in the current issue of the trade journal "Nature Communications."
Graphene ribbons that are only a few atoms wide, so-called graphene nanoribbons, have special electrical properties that make them promising candidates for the...
08.12.2017 | Event News
07.12.2017 | Event News
05.12.2017 | Event News
08.12.2017 | Life Sciences
08.12.2017 | Information Technology
08.12.2017 | Information Technology