Good to the last amino acid
This is C. elegans. Its genome was thought to have been completed until a WUSTL computer scientist applied a computer software program he developed which found scores more genes and predicted the existence of over a thousand additional genes.
A computer scientist at Washington University in St. Louis has applied software that he has developed to the genome of a worm and has found 150 genes that were missed by previous genome analysis methods. Moreover, using the software, he and his colleagues have developed predictions for the existence of a whopping 1, 119 more genes.
Michael Brent, Ph.D., Washington University professor of computer science and engineering, used his unique software, TWINSCAN, on the genome of Caenorhabditis elegans (C. elegans). The genome of another nematode C. briggsae, was also used to determine which parts of the sequence have changed since the nearest common ancestor of the two species. He found first of all that TWINSCAN predicted 60 percent of the genes in the C. elegans genome exactly, right own to the last amino acid.
Tony Fitzpatrick | EurekAlert!
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