The Biaffin GmbH & Co KG is one of nine European partners of a new EU "Specifically Targeted Research Project (STREP)" started on 1 st of January 2005 for a period of three years. The project is entitled "Function of small RNAs across kingdoms (FOSRAK)" to study the hitherto unrecognised cellular role of various classes of short non-coding RNAs in regulating gene expression in a variety of organisms across different biological kingdoms like eubacteria, protists, plants and animals.
The aim of this project is the advancement of knowledge of how these riboregulators and their interacting protein components are integrated into the general network of gene expression and in developmental processes. Little is known of how the short heterochromatic RNAs (sh RNAs) interact with chromatin, short interference RNAs (si RNAs) modulate mRNA stabiltity, micro RNAs (mi RNAs) influence the level of translation and small nucleolar RNAs (sno RNAs) are involved in postranscriptional modification of ribosomal and spliceosomal small nucleolar RNAs (sn RNAs). Small RNAs from pathogenic bacteria and human small RNAs that are implicated in human diseases and cancer formation are a special focus for future therapeutic intervention.
Biaffin provides the sophisticated instrumentation of surface plasmon resonance technology coupled to mass spectrometry (BIA-MS; BIA: biomolecular interaction analysis) to identify and kinetically characterise molecular targets of regulatory RNAs. To elucidate the mechanism of RNA interaction with their targets the structural and functional aspects of small regulatory RNAs has to be studied in detail. Innovation aspects will be created to use the BIA technology for studying RNA-RNA and RNA-protein interactions.
Could this protein protect people against coronary artery disease?
17.11.2017 | University of North Carolina Health Care
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17.11.2017 | Max-Planck-Institut für chemische Ökologie
The formation of stars in distant galaxies is still largely unexplored. For the first time, astron-omers at the University of Geneva have now been able to closely observe a star system six billion light-years away. In doing so, they are confirming earlier simulations made by the University of Zurich. One special effect is made possible by the multiple reflections of images that run through the cosmos like a snake.
Today, astronomers have a pretty accurate idea of how stars were formed in the recent cosmic past. But do these laws also apply to older galaxies? For around a...
Just because someone is smart and well-motivated doesn't mean he or she can learn the visual skills needed to excel at tasks like matching fingerprints, interpreting medical X-rays, keeping track of aircraft on radar displays or forensic face matching.
That is the implication of a new study which shows for the first time that there is a broad range of differences in people's visual ability and that these...
Computer Tomography (CT) is a standard procedure in hospitals, but so far, the technology has not been suitable for imaging extremely small objects. In PNAS, a team from the Technical University of Munich (TUM) describes a Nano-CT device that creates three-dimensional x-ray images at resolutions up to 100 nanometers. The first test application: Together with colleagues from the University of Kassel and Helmholtz-Zentrum Geesthacht the researchers analyzed the locomotory system of a velvet worm.
During a CT analysis, the object under investigation is x-rayed and a detector measures the respective amount of radiation absorbed from various angles....
The quantum world is fragile; error correction codes are needed to protect the information stored in a quantum object from the deteriorating effects of noise. Quantum physicists in Innsbruck have developed a protocol to pass quantum information between differently encoded building blocks of a future quantum computer, such as processors and memories. Scientists may use this protocol in the future to build a data bus for quantum computers. The researchers have published their work in the journal Nature Communications.
Future quantum computers will be able to solve problems where conventional computers fail today. We are still far away from any large-scale implementation,...
Pillared graphene would transfer heat better if the theoretical material had a few asymmetric junctions that caused wrinkles, according to Rice University...
15.11.2017 | Event News
15.11.2017 | Event News
30.10.2017 | Event News
17.11.2017 | Physics and Astronomy
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17.11.2017 | Studies and Analyses