The Biaffin GmbH & Co KG is one of nine European partners of a new EU "Specifically Targeted Research Project (STREP)" started on 1 st of January 2005 for a period of three years. The project is entitled "Function of small RNAs across kingdoms (FOSRAK)" to study the hitherto unrecognised cellular role of various classes of short non-coding RNAs in regulating gene expression in a variety of organisms across different biological kingdoms like eubacteria, protists, plants and animals.
The aim of this project is the advancement of knowledge of how these riboregulators and their interacting protein components are integrated into the general network of gene expression and in developmental processes. Little is known of how the short heterochromatic RNAs (sh RNAs) interact with chromatin, short interference RNAs (si RNAs) modulate mRNA stabiltity, micro RNAs (mi RNAs) influence the level of translation and small nucleolar RNAs (sno RNAs) are involved in postranscriptional modification of ribosomal and spliceosomal small nucleolar RNAs (sn RNAs). Small RNAs from pathogenic bacteria and human small RNAs that are implicated in human diseases and cancer formation are a special focus for future therapeutic intervention.
Biaffin provides the sophisticated instrumentation of surface plasmon resonance technology coupled to mass spectrometry (BIA-MS; BIA: biomolecular interaction analysis) to identify and kinetically characterise molecular targets of regulatory RNAs. To elucidate the mechanism of RNA interaction with their targets the structural and functional aspects of small regulatory RNAs has to be studied in detail. Innovation aspects will be created to use the BIA technology for studying RNA-RNA and RNA-protein interactions.
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Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
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COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
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