A newly discovered virus may be responsible for many respiratory tract illnesses in infants and children, and may be associated with an important multi-organ disease whose cause has remained a mystery for decades, according to articles in the Feb. 15 issue of The Journal of Infectious Diseases, now available online. The virus is one of the numerous coronaviruses, most of which infect animals. In humans, coronaviruses have been known primarily for causing colds or, more recently, severe acute respiratory syndrome (SARS). Genetic evidence now suggests that a previously unknown coronavirus may account for some of the many respiratory diseases for which a causative agent is unidentified, and may have a role in Kawasaki disease, the most common cause of acquired heart disease in children in developed countries.
In the first of two studies, Jeffrey S. Kahn and co-workers at Yale University used molecular probes targeting a gene that is common in human and animal coronaviruses to screen hundreds of specimens for coronavirus genetic material. Ultimately, two specimens were identified in which the sequence of chemical building blocks of the gene differed from that of known human coronaviruses. The Yale investigators, terming the novel virus indicated by their findings the New Haven coronavirus, then used probes specific for the virus to screen respiratory specimens from 895 symptomatic children under age 5 who had tested negative for other viral infections. They found 79 (9 percent) who were positive for the new virus, nine of whom were subsequently found to have evidence of recent infection with another virus as well. Of the remaining 67 patients for whom clinical data were available, signs and symptoms of infection with the new virus included fever, cough, runny nose, rapid breathing, abnormal breath sounds, and hypoxia; 35 had an underlying condition, such as prematurity (19 patients). Indeed, 11 of those infected with the new coronavirus were newborns hospitalized in intensive care.
Analysis of the New Haven coronavirus’s genetic structure showed many similarities to that of a coronavirus recently identified by two groups in the Netherlands, suggesting that the virus may have worldwide distribution.
Steve Baragona | EurekAlert!
Researchers identify potentially druggable mutant p53 proteins that promote cancer growth
09.12.2016 | Cold Spring Harbor Laboratory
Plant-based substance boosts eyelash growth
09.12.2016 | Fraunhofer-Institut für Angewandte Polymerforschung IAP
Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
16.11.2016 | Event News
01.11.2016 | Event News
14.10.2016 | Event News
09.12.2016 | Life Sciences
09.12.2016 | Ecology, The Environment and Conservation
09.12.2016 | Health and Medicine