By using a device only six-millionths of a meter long, researchers at Cornell University have been able to detect the presence of as few as a half-dozen viruses -- and they believe the device is sensitive enough to notice just one.
The research could lead to simple detectors capable of differentiating between a wide variety of pathogens,i ncluding viruses, bacteria and toxic organic chemicals. The experiment, an extension of earlier work in which similar devices were used to detect the mass of a single bacterium, is reported in a paper, "Virus detection using nanoelectromechanical devices," in the September 27, 2004, issue ofApplied Physics Letters by Cornell research associate Rob Ilic of the Cornell NanoScale Facility (CNF), Yanou Yang, a Cornell graduate student in biomedical engineering, and Harold Craighead, Cornell professor of applied and engineering physics. The work was done with the assistance of Michael Shuler, Cornell professor of chemical and biological engineering, and microbiologist Gary Blissard of the Boyce Thompson Institute for Plant Research on the Cornell campus.
At CNF, the researchers created arrays of tiny silicon paddles from 6 to 10 micrometers (millionths of a meter) long, half a micrometer wide, and about 150 nanometers (billionths of a meter) thick, with a one-micrometer square pad at the end. Think of a tiny fly-swatter mounted by its handle like a diving board. A large array of paddles were mounted on a piezoelectric crystal that can be made to vibrate at frequencies on the order of 5 to 10 megaHertz (mHz). The experimenters then varied the frequency of vibration of the crystal. When it matched the paddles resonant frequency, the paddles began to vibrate, as measured by focusing a laser on the paddles and noting the change in reflected light, a process called optical interferometry.
A Map of the Cell’s Power Station
18.08.2017 | Albert-Ludwigs-Universität Freiburg im Breisgau
On the way to developing a new active ingredient against chronic infections
18.08.2017 | Deutsches Zentrum für Infektionsforschung
Whether you call it effervescent, fizzy, or sparkling, carbonated water is making a comeback as a beverage. Aside from quenching thirst, researchers at the University of Illinois at Urbana-Champaign have discovered a new use for these "bubbly" concoctions that will have major impact on the manufacturer of the world's thinnest, flattest, and one most useful materials -- graphene.
As graphene's popularity grows as an advanced "wonder" material, the speed and quality at which it can be manufactured will be paramount. With that in mind,...
Physicists at the University of Bonn have managed to create optical hollows and more complex patterns into which the light of a Bose-Einstein condensate flows. The creation of such highly low-loss structures for light is a prerequisite for complex light circuits, such as for quantum information processing for a new generation of computers. The researchers are now presenting their results in the journal Nature Photonics.
Light particles (photons) occur as tiny, indivisible portions. Many thousands of these light portions can be merged to form a single super-photon if they are...
For the first time, scientists have shown that circular RNA is linked to brain function. When a RNA molecule called Cdr1as was deleted from the genome of mice, the animals had problems filtering out unnecessary information – like patients suffering from neuropsychiatric disorders.
While hundreds of circular RNAs (circRNAs) are abundant in mammalian brains, one big question has remained unanswered: What are they actually good for? In the...
An experimental small satellite has successfully collected and delivered data on a key measurement for predicting changes in Earth's climate.
The Radiometer Assessment using Vertically Aligned Nanotubes (RAVAN) CubeSat was launched into low-Earth orbit on Nov. 11, 2016, in order to test new...
A study led by scientists of the Max Planck Institute for the Structure and Dynamics of Matter (MPSD) at the Center for Free-Electron Laser Science in Hamburg presents evidence of the coexistence of superconductivity and “charge-density-waves” in compounds of the poorly-studied family of bismuthates. This observation opens up new perspectives for a deeper understanding of the phenomenon of high-temperature superconductivity, a topic which is at the core of condensed matter research since more than 30 years. The paper by Nicoletti et al has been published in the PNAS.
Since the beginning of the 20th century, superconductivity had been observed in some metals at temperatures only a few degrees above the absolute zero (minus...
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