By using a device only six-millionths of a meter long, researchers at Cornell University have been able to detect the presence of as few as a half-dozen viruses -- and they believe the device is sensitive enough to notice just one.
The research could lead to simple detectors capable of differentiating between a wide variety of pathogens,i ncluding viruses, bacteria and toxic organic chemicals. The experiment, an extension of earlier work in which similar devices were used to detect the mass of a single bacterium, is reported in a paper, "Virus detection using nanoelectromechanical devices," in the September 27, 2004, issue ofApplied Physics Letters by Cornell research associate Rob Ilic of the Cornell NanoScale Facility (CNF), Yanou Yang, a Cornell graduate student in biomedical engineering, and Harold Craighead, Cornell professor of applied and engineering physics. The work was done with the assistance of Michael Shuler, Cornell professor of chemical and biological engineering, and microbiologist Gary Blissard of the Boyce Thompson Institute for Plant Research on the Cornell campus.
At CNF, the researchers created arrays of tiny silicon paddles from 6 to 10 micrometers (millionths of a meter) long, half a micrometer wide, and about 150 nanometers (billionths of a meter) thick, with a one-micrometer square pad at the end. Think of a tiny fly-swatter mounted by its handle like a diving board. A large array of paddles were mounted on a piezoelectric crystal that can be made to vibrate at frequencies on the order of 5 to 10 megaHertz (mHz). The experimenters then varied the frequency of vibration of the crystal. When it matched the paddles resonant frequency, the paddles began to vibrate, as measured by focusing a laser on the paddles and noting the change in reflected light, a process called optical interferometry.
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Salmonellae are dangerous pathogens that enter the body via contaminated food and can cause severe infections. But these bacteria are also known to target...
University of Maryland researchers contribute to historic detection of gravitational waves and light created by event
On August 17, 2017, at 12:41:04 UTC, scientists made the first direct observation of a merger between two neutron stars--the dense, collapsed cores that remain...
Seven new papers describe the first-ever detection of light from a gravitational wave source. The event, caused by two neutron stars colliding and merging together, was dubbed GW170817 because it sent ripples through space-time that reached Earth on 2017 August 17. Around the world, hundreds of excited astronomers mobilized quickly and were able to observe the event using numerous telescopes, providing a wealth of new data.
Previous detections of gravitational waves have all involved the merger of two black holes, a feat that won the 2017 Nobel Prize in Physics earlier this month....
Material defects in end products can quickly result in failures in many areas of industry, and have a massive impact on the safe use of their products. This is why, in the field of quality assurance, intelligent, nondestructive sensor systems play a key role. They allow testing components and parts in a rapid and cost-efficient manner without destroying the actual product or changing its surface. Experts from the Fraunhofer IZFP in Saarbrücken will be presenting two exhibits at the Blechexpo in Stuttgart from 7–10 November 2017 that allow fast, reliable, and automated characterization of materials and detection of defects (Hall 5, Booth 5306).
When quality testing uses time-consuming destructive test methods, it can result in enormous costs due to damaging or destroying the products. And given that...
Using a new cooling technique MPQ scientists succeed at observing collisions in a dense beam of cold and slow dipolar molecules.
How do chemical reactions proceed at extremely low temperatures? The answer requires the investigation of molecular samples that are cold, dense, and slow at...
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