By using a device only six-millionths of a meter long, researchers at Cornell University have been able to detect the presence of as few as a half-dozen viruses -- and they believe the device is sensitive enough to notice just one.
The research could lead to simple detectors capable of differentiating between a wide variety of pathogens,i ncluding viruses, bacteria and toxic organic chemicals. The experiment, an extension of earlier work in which similar devices were used to detect the mass of a single bacterium, is reported in a paper, "Virus detection using nanoelectromechanical devices," in the September 27, 2004, issue ofApplied Physics Letters by Cornell research associate Rob Ilic of the Cornell NanoScale Facility (CNF), Yanou Yang, a Cornell graduate student in biomedical engineering, and Harold Craighead, Cornell professor of applied and engineering physics. The work was done with the assistance of Michael Shuler, Cornell professor of chemical and biological engineering, and microbiologist Gary Blissard of the Boyce Thompson Institute for Plant Research on the Cornell campus.
At CNF, the researchers created arrays of tiny silicon paddles from 6 to 10 micrometers (millionths of a meter) long, half a micrometer wide, and about 150 nanometers (billionths of a meter) thick, with a one-micrometer square pad at the end. Think of a tiny fly-swatter mounted by its handle like a diving board. A large array of paddles were mounted on a piezoelectric crystal that can be made to vibrate at frequencies on the order of 5 to 10 megaHertz (mHz). The experimenters then varied the frequency of vibration of the crystal. When it matched the paddles resonant frequency, the paddles began to vibrate, as measured by focusing a laser on the paddles and noting the change in reflected light, a process called optical interferometry.
Researchers identify potentially druggable mutant p53 proteins that promote cancer growth
09.12.2016 | Cold Spring Harbor Laboratory
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09.12.2016 | Fraunhofer-Institut für Angewandte Polymerforschung IAP
Physicists of the University of Würzburg have made an astonishing discovery in a specific type of topological insulators. The effect is due to the structure of the materials used. The researchers have now published their work in the journal Science.
Topological insulators are currently the hot topic in physics according to the newspaper Neue Zürcher Zeitung. Only a few weeks ago, their importance was...
In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
“Our Quantum droplets are in the gas phase but they still drop like a rock,” explains experimental physicist Francesca Ferlaino when talking about the...
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