Certain genes are expressed differently in people with depression
Researchers have found altered gene activity in people who suffer from major depression, a discovery that may one day help doctors better diagnose and treat the condition. The research, conducted by a consortium of four universities, appears this week in the online edition of the Proceedings of the National Academy of Sciences USA (PNAS). Scientists found that the fibroblast growth factor system, which is a family of proteins involved in the growth, development and maintenance of nerve cells, had an overall decrease in levels in patients who had major depressive disorder. Proteins are the products of gene expression.
"This study is the first to implicate this particular family of gene products in major depression," said Edward G. Jones, professor of psychiatry and director of the Center for Neuroscience at UC Davis and a principal investigator of the study. "The fibroblast growth factor system is now important to consider when looking for causes of mood disorders."
Carole Gan | EurekAlert!
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