Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

New Model Helps Diabetes Research

17.08.2004


Scientists at the Babraham Institute are developing new methods to aid research into the causes of diabetes, a condition suffered by around 2.5 million people in the UK. A new study, published in The Journal of Clinical Investigation, describes an effective model of a rare form of the disease called transient neonatal diabetes mellitus (TNDM), which affects approximately 1 in 600,000 newborn babies. Babies born with TNDM initially cannot produce insulin, but symptoms disappear after about 3 months. However two-thirds of those affected will develop diabetes later in life, usually in their teens.



The mouse model, developed by the research group headed by Dr Gavin Kelsey, shows disappearing and reappearing diabetes similar to that seen in TDNM, and makes the examination of the faulty insulin-producing cells of the pancreas much more straightforward. A reduction in the levels of several key chemicals involved in the development of the pancreas has already been shown.

Dr Kelsey comments “Although a rare form of diabetes, TNDM is important to our understanding of diabetes because the defective gene has been identified. A model for TNDM, such as the one produced at Babraham, will allow us to study in detail the problems that arise in the insulin-producing cells when this defective gene is expressed.”

Emma Southern | alfa
Further information:
http://www.bbsrc.ac.uk

More articles from Life Sciences:

nachricht CRISPR meets single-cell sequencing in new screening method
19.01.2017 | CeMM Forschungszentrum für Molekulare Medizin der Österreichischen Akademie der Wissenschaften

nachricht Toward a 'smart' patch that automatically delivers insulin when needed
18.01.2017 | American Chemical Society

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Traffic jam in empty space

New success for Konstanz physicists in studying the quantum vacuum

An important step towards a completely new experimental access to quantum physics has been made at University of Konstanz. The team of scientists headed by...

Im Focus: How gut bacteria can make us ill

HZI researchers decipher infection mechanisms of Yersinia and immune responses of the host

Yersiniae cause severe intestinal infections. Studies using Yersinia pseudotuberculosis as a model organism aim to elucidate the infection mechanisms of these...

Im Focus: Interfacial Superconductivity: Magnetic and superconducting order revealed simultaneously

Researchers from the University of Hamburg in Germany, in collaboration with colleagues from the University of Aarhus in Denmark, have synthesized a new superconducting material by growing a few layers of an antiferromagnetic transition-metal chalcogenide on a bismuth-based topological insulator, both being non-superconducting materials.

While superconductivity and magnetism are generally believed to be mutually exclusive, surprisingly, in this new material, superconducting correlations...

Im Focus: Studying fundamental particles in materials

Laser-driving of semimetals allows creating novel quasiparticle states within condensed matter systems and switching between different states on ultrafast time scales

Studying properties of fundamental particles in condensed matter systems is a promising approach to quantum field theory. Quasiparticles offer the opportunity...

Im Focus: Designing Architecture with Solar Building Envelopes

Among the general public, solar thermal energy is currently associated with dark blue, rectangular collectors on building roofs. Technologies are needed for aesthetically high quality architecture which offer the architect more room for manoeuvre when it comes to low- and plus-energy buildings. With the “ArKol” project, researchers at Fraunhofer ISE together with partners are currently developing two façade collectors for solar thermal energy generation, which permit a high degree of design flexibility: a strip collector for opaque façade sections and a solar thermal blind for transparent sections. The current state of the two developments will be presented at the BAU 2017 trade fair.

As part of the “ArKol – development of architecturally highly integrated façade collectors with heat pipes” project, Fraunhofer ISE together with its partners...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Sustainable Water use in Agriculture in Eastern Europe and Central Asia

19.01.2017 | Event News

12V, 48V, high-voltage – trends in E/E automotive architecture

10.01.2017 | Event News

2nd Conference on Non-Textual Information on 10 and 11 May 2017 in Hannover

09.01.2017 | Event News

 
Latest News

Molecule flash mob

19.01.2017 | Physics and Astronomy

Rabies viruses reveal wiring in transparent brains

19.01.2017 | Health and Medicine

Global threat to primates concerns us all

19.01.2017 | Ecology, The Environment and Conservation

VideoLinks
B2B-VideoLinks
More VideoLinks >>>