Different combinations of genetic mutations may give rise to diverse human traits, including complex diseases such as schizophrenia, say scientists at the University of Toronto and McGill University in Montreal.
Drs. Brenda Andrews and Charles Boone of U of T and Howard Bussey of McGill used simple yeast cells to demonstrate that there are many different combinations of genetic mutations that can lead to cell death or reduced cell fitness. The research team will now focus on mapping gene interactions for those yeast genes that are similar to human genes. Their study appears in the Feb. 6 issue of the journal Science.
The researchers crossed a yeast strain carrying a mutation in a particular gene of interest with a collection or "array" of other yeast strains to determine which gene pairs were lethal. The team studied more than 4,000 of these interactions involving gene pairs and was able to provide a large scale "genetic interaction network" that provokes new ideas about how genes interact to produce different traits.
Elaine Smith | University of Toronto
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In recent years, lasers with ultrashort pulses (USP) down to the femtosecond range have become established on an industrial scale. They could advance some applications with the much-lauded “cold ablation” – if that meant they would then achieve more throughput. A new generation of process engineering that will address this issue in particular will be discussed at the “4th UKP Workshop – Ultrafast Laser Technology” in April 2017.
Even back in the 1990s, scientists were comparing materials processing with nanosecond, picosecond and femtosesecond pulses. The result was surprising:...
Have you ever wondered how you see the world? Vision is about photons of light, which are packets of energy, interacting with the atoms or molecules in what...
A multi-institutional research collaboration has created a novel approach for fabricating three-dimensional micro-optics through the shape-defined formation of porous silicon (PSi), with broad impacts in integrated optoelectronics, imaging, and photovoltaics.
Working with colleagues at Stanford and The Dow Chemical Company, researchers at the University of Illinois at Urbana-Champaign fabricated 3-D birefringent...
In experiments with magnetic atoms conducted at extremely low temperatures, scientists have demonstrated a unique phase of matter: The atoms form a new type of quantum liquid or quantum droplet state. These so called quantum droplets may preserve their form in absence of external confinement because of quantum effects. The joint team of experimental physicists from Innsbruck and theoretical physicists from Hannover report on their findings in the journal Physical Review X.
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The Max Planck Institute for Physics (MPP) is opening up a new research field. A workshop from November 21 - 22, 2016 will mark the start of activities for an innovative axion experiment. Axions are still only purely hypothetical particles. Their detection could solve two fundamental problems in particle physics: What dark matter consists of and why it has not yet been possible to directly observe a CP violation for the strong interaction.
The “MADMAX” project is the MPP’s commitment to axion research. Axions are so far only a theoretical prediction and are difficult to detect: on the one hand,...
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