A group of scientists led by Dr. Elaine Fuchs at the Howard Hughes Medical Institute at the Rockefeller University have uncovered an unexpected new role for the well-known transcription factor, GATA-3, in hair follicle development. GATA-3 was previously identified for its role in coaxing hematopoietic stem cells towards a T-cell fate. Now, Dr. Fuchs and colleagues reveal that GATA-3 is also involved in epidermal stem cell specification. This finding lends valuable insight into hair follicle generation, and highlights intriguing parallels between the molecular cues that direct cell fate specification in the skin and the immune system.
Each of the roughly 5 million hair follicles that cover the adult human body has a similar structure. The hair follicle consists of a multi-layered hair shaft, the outermost layer of which is referred to as the cuticle. Below the skin surface, the cuticle is surrounded by an inner root sheath (IRS).
"The IRS acts as a channel, functioning to guide the developing hair shaft up to the skin surface. Without the channel, the hair does not develop properly," explains professor Fuchs.
Heather Cosel | EurekAlert!
Seeking balanced networks: how neurons adjust their proteins during homeostatic scaling.
24.10.2016 | Max-Planck-Institut für Hirnforschung
Novel mechanisms of action discovered for the skin cancer medication Imiquimod
21.10.2016 | Technische Universität München
Researchers from the Institute for Quantum Computing (IQC) at the University of Waterloo led the development of a new extensible wiring technique capable of controlling superconducting quantum bits, representing a significant step towards to the realization of a scalable quantum computer.
"The quantum socket is a wiring method that uses three-dimensional wires based on spring-loaded pins to address individual qubits," said Jeremy Béjanin, a PhD...
In a paper in Scientific Reports, a research team at Worcester Polytechnic Institute describes a novel light-activated phenomenon that could become the basis for applications as diverse as microscopic robotic grippers and more efficient solar cells.
A research team at Worcester Polytechnic Institute (WPI) has developed a revolutionary, light-activated semiconductor nanocomposite material that can be used...
By forcefully embedding two silicon atoms in a diamond matrix, Sandia researchers have demonstrated for the first time on a single chip all the components needed to create a quantum bridge to link quantum computers together.
"People have already built small quantum computers," says Sandia researcher Ryan Camacho. "Maybe the first useful one won't be a single giant quantum computer...
COMPAMED has become the leading international marketplace for suppliers of medical manufacturing. The trade fair, which takes place every November and is co-located to MEDICA in Dusseldorf, has been steadily growing over the past years and shows that medical technology remains a rapidly growing market.
In 2016, the joint pavilion by the IVAM Microtechnology Network, the Product Market “High-tech for Medical Devices”, will be located in Hall 8a again and will...
'Ferroelectric' materials can switch between different states of electrical polarization in response to an external electric field. This flexibility means they show promise for many applications, for example in electronic devices and computer memory. Current ferroelectric materials are highly valued for their thermal and chemical stability and rapid electro-mechanical responses, but creating a material that is scalable down to the tiny sizes needed for technologies like silicon-based semiconductors (Si-based CMOS) has proven challenging.
Now, Hiroshi Funakubo and co-workers at the Tokyo Institute of Technology, in collaboration with researchers across Japan, have conducted experiments to...
14.10.2016 | Event News
14.10.2016 | Event News
12.10.2016 | Event News
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21.10.2016 | Health and Medicine
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