Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Growing green gold

06.06.2003


A new way to make gold form inside the cells of a micro-organism is published today in the Institute of Physics journal Nanotechnology. Researchers from the National Chemical Laboratory and the Armed Forces Medical College, both in Pune, India, have been using “green chemistry” to develop an eco-friendly way to make tiny gold particles without using toxic chemicals.



Such gold nanoparticles of uniform size can be used in labelling proteins, nucleic acids and other biomolecules, which could lead to new ways of detecting disease, controlling genes and enzymes, and delivering therapeutic drugs directly to the nucleus of the cell. The technology can also be used in developing nanomaterials and nanoelectronics.

The research group took a micro-organism called Rhodococcus from a fig tree, and exposed it to a liquid containing gold ions (which are electrically charged gold particles, rather than neutral ones). They found that the micro-organism caused the gold ions to gain electrons, thereby forming gold nanoparticles within the micro-organism’s cells. These nanoparticles are more concentrated and more uniform in size than particles biosynthesised by previous methods that used a fungus. Although the exact reaction that causes the gold to form is not yet fully known, the group believe that the Rhodococcus species gives better results because it is a certain type of micro-organism (an actinomycete) that shows characteristics of both bacteria and fungi, rather than just being a fungus.



“I am extremely pleased with the formation of these gold nanoparticles. They are mainly between about nine and twelve nanometres in diameter, with a few larger particles. That’s about eight thousand times smaller than a human hair,” said Dr. Murali Sastry from the National Chemical Laboratory, India. “This is much more uniform than the particles formed using other biological methods. Having uniformly sized particles will be needed if we are to use this method in biodiagnosis using gold nanoparticles or to deliver therapeutic drugs.”

Following the biosynthesis of gold nanoparticles in Rhodococcus species, its cells continued to multiply normally, as the ions used were not toxic to the cells – which is important as more gold would be formed as the cells multiplied.

The group will soon be looking into making the nanoparticles on a large scale, which could be attained by genetically modifying actinomycetes to produce more of the enzymes which cause the gold to form.

Michelle Cain | alfa
Further information:
http://stacks.iop.org/Nano/14/824

More articles from Life Sciences:

nachricht Zeolite catalysts pave the road to decentral chemical processes Confined space increases reactivity
28.06.2017 | Technische Universität München

nachricht For a chimpanzee, one good turn deserves another
27.06.2017 | Max-Planck-Institut für Mathematik in den Naturwissenschaften (MPIMIS)

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Can we see monkeys from space? Emerging technologies to map biodiversity

An international team of scientists has proposed a new multi-disciplinary approach in which an array of new technologies will allow us to map biodiversity and the risks that wildlife is facing at the scale of whole landscapes. The findings are published in Nature Ecology and Evolution. This international research is led by the Kunming Institute of Zoology from China, University of East Anglia, University of Leicester and the Leibniz Institute for Zoo and Wildlife Research.

Using a combination of satellite and ground data, the team proposes that it is now possible to map biodiversity with an accuracy that has not been previously...

Im Focus: Climate satellite: Tracking methane with robust laser technology

Heatwaves in the Arctic, longer periods of vegetation in Europe, severe floods in West Africa – starting in 2021, scientists want to explore the emissions of the greenhouse gas methane with the German-French satellite MERLIN. This is made possible by a new robust laser system of the Fraunhofer Institute for Laser Technology ILT in Aachen, which achieves unprecedented measurement accuracy.

Methane is primarily the result of the decomposition of organic matter. The gas has a 25 times greater warming potential than carbon dioxide, but is not as...

Im Focus: How protons move through a fuel cell

Hydrogen is regarded as the energy source of the future: It is produced with solar power and can be used to generate heat and electricity in fuel cells. Empa researchers have now succeeded in decoding the movement of hydrogen ions in crystals – a key step towards more efficient energy conversion in the hydrogen industry of tomorrow.

As charge carriers, electrons and ions play the leading role in electrochemical energy storage devices and converters such as batteries and fuel cells. Proton...

Im Focus: A unique data centre for cosmological simulations

Scientists from the Excellence Cluster Universe at the Ludwig-Maximilians-Universität Munich have establised "Cosmowebportal", a unique data centre for cosmological simulations located at the Leibniz Supercomputing Centre (LRZ) of the Bavarian Academy of Sciences. The complete results of a series of large hydrodynamical cosmological simulations are available, with data volumes typically exceeding several hundred terabytes. Scientists worldwide can interactively explore these complex simulations via a web interface and directly access the results.

With current telescopes, scientists can observe our Universe’s galaxies and galaxy clusters and their distribution along an invisible cosmic web. From the...

Im Focus: Scientists develop molecular thermometer for contactless measurement using infrared light

Temperature measurements possible even on the smallest scale / Molecular ruby for use in material sciences, biology, and medicine

Chemists at Johannes Gutenberg University Mainz (JGU) in cooperation with researchers of the German Federal Institute for Materials Research and Testing (BAM)...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

Event News

Plants are networkers

19.06.2017 | Event News

Digital Survival Training for Executives

13.06.2017 | Event News

Global Learning Council Summit 2017

13.06.2017 | Event News

 
Latest News

Extensive Funding for Research on Chromatin, Adrenal Gland, and Cancer Therapy

28.06.2017 | Awards Funding

Predicting eruptions using satellites and math

28.06.2017 | Earth Sciences

Extremely fine measurements of motion in orbiting supermassive black holes

28.06.2017 | Physics and Astronomy

VideoLinks
B2B-VideoLinks
More VideoLinks >>>