Forum for Science, Industry and Business

Sponsored by:     3M 
Search our Site:

 

Growing green gold

06.06.2003


A new way to make gold form inside the cells of a micro-organism is published today in the Institute of Physics journal Nanotechnology. Researchers from the National Chemical Laboratory and the Armed Forces Medical College, both in Pune, India, have been using “green chemistry” to develop an eco-friendly way to make tiny gold particles without using toxic chemicals.



Such gold nanoparticles of uniform size can be used in labelling proteins, nucleic acids and other biomolecules, which could lead to new ways of detecting disease, controlling genes and enzymes, and delivering therapeutic drugs directly to the nucleus of the cell. The technology can also be used in developing nanomaterials and nanoelectronics.

The research group took a micro-organism called Rhodococcus from a fig tree, and exposed it to a liquid containing gold ions (which are electrically charged gold particles, rather than neutral ones). They found that the micro-organism caused the gold ions to gain electrons, thereby forming gold nanoparticles within the micro-organism’s cells. These nanoparticles are more concentrated and more uniform in size than particles biosynthesised by previous methods that used a fungus. Although the exact reaction that causes the gold to form is not yet fully known, the group believe that the Rhodococcus species gives better results because it is a certain type of micro-organism (an actinomycete) that shows characteristics of both bacteria and fungi, rather than just being a fungus.



“I am extremely pleased with the formation of these gold nanoparticles. They are mainly between about nine and twelve nanometres in diameter, with a few larger particles. That’s about eight thousand times smaller than a human hair,” said Dr. Murali Sastry from the National Chemical Laboratory, India. “This is much more uniform than the particles formed using other biological methods. Having uniformly sized particles will be needed if we are to use this method in biodiagnosis using gold nanoparticles or to deliver therapeutic drugs.”

Following the biosynthesis of gold nanoparticles in Rhodococcus species, its cells continued to multiply normally, as the ions used were not toxic to the cells – which is important as more gold would be formed as the cells multiplied.

The group will soon be looking into making the nanoparticles on a large scale, which could be attained by genetically modifying actinomycetes to produce more of the enzymes which cause the gold to form.

Michelle Cain | alfa
Further information:
http://stacks.iop.org/Nano/14/824

More articles from Life Sciences:

nachricht Building a brain, cell by cell: Researchers make a mini neuron network (of two)
23.05.2018 | Institute of Industrial Science, The University of Tokyo

nachricht Research reveals how order first appears in liquid crystals
23.05.2018 | Brown University

All articles from Life Sciences >>>

The most recent press releases about innovation >>>

Die letzten 5 Focus-News des innovations-reports im Überblick:

Im Focus: Molecular switch will facilitate the development of pioneering electro-optical devices

A research team led by physicists at the Technical University of Munich (TUM) has developed molecular nanoswitches that can be toggled between two structurally different states using an applied voltage. They can serve as the basis for a pioneering class of devices that could replace silicon-based components with organic molecules.

The development of new electronic technologies drives the incessant reduction of functional component sizes. In the context of an international collaborative...

Im Focus: LZH showcases laser material processing of tomorrow at the LASYS 2018

At the LASYS 2018, from June 5th to 7th, the Laser Zentrum Hannover e.V. (LZH) will be showcasing processes for the laser material processing of tomorrow in hall 4 at stand 4E75. With blown bomb shells the LZH will present first results of a research project on civil security.

At this year's LASYS, the LZH will exhibit light-based processes such as cutting, welding, ablation and structuring as well as additive manufacturing for...

Im Focus: Self-illuminating pixels for a new display generation

There are videos on the internet that can make one marvel at technology. For example, a smartphone is casually bent around the arm or a thin-film display is rolled in all directions and with almost every diameter. From the user's point of view, this looks fantastic. From a professional point of view, however, the question arises: Is that already possible?

At Display Week 2018, scientists from the Fraunhofer Institute for Applied Polymer Research IAP will be demonstrating today’s technological possibilities and...

Im Focus: Explanation for puzzling quantum oscillations has been found

So-called quantum many-body scars allow quantum systems to stay out of equilibrium much longer, explaining experiment | Study published in Nature Physics

Recently, researchers from Harvard and MIT succeeded in trapping a record 53 atoms and individually controlling their quantum state, realizing what is called a...

Im Focus: Dozens of binaries from Milky Way's globular clusters could be detectable by LISA

Next-generation gravitational wave detector in space will complement LIGO on Earth

The historic first detection of gravitational waves from colliding black holes far outside our galaxy opened a new window to understanding the universe. A...

All Focus news of the innovation-report >>>

Anzeige

Anzeige

VideoLinks
Industry & Economy
Event News

Save the date: Forum European Neuroscience – 07-11 July 2018 in Berlin, Germany

02.05.2018 | Event News

Invitation to the upcoming "Current Topics in Bioinformatics: Big Data in Genomics and Medicine"

13.04.2018 | Event News

Unique scope of UV LED technologies and applications presented in Berlin: ICULTA-2018

12.04.2018 | Event News

 
Latest News

Molecular switch will facilitate the development of pioneering electro-optical devices

24.05.2018 | Power and Electrical Engineering

Research reveals how order first appears in liquid crystals

23.05.2018 | Life Sciences

Space-like gravity weakens biochemical signals in muscle formation

23.05.2018 | Life Sciences

VideoLinks
Science & Research
Overview of more VideoLinks >>>